Egr-1 is an immediate-early response gene induced transiently and ubiquitously by
mitogenic stimuli and also regulated in response to signals that initiate differentiation. The …

Publisher Summary This chapter discusses the early growth response protein (Egr) gene
family and its most extensively characterized member, Egr-1, first identified as an immediate …

Most of what is known of the Egr-1 DNA binding site GCGGGGGCG was originally identified
by experiments using DNA sequences and bacterially expressed or in vitro translated EGR …

Transcript elongation by polymerase II paused at the Egr1 promoter is activated by mitogen-
activated protein kinase phosphorylation of the ternary complex factor (TCF) ELK1 bound at …

Early growth response gene-1 (Egr-1) is a mouse gene displaying fos-like induction kinetics
in diverse cell types following mitogenic stimulation. Egr-1 encodes a protein with" zinc …

The transcription factor, Early growth response-1, Egr-1, occurs in several forms differing in
length due to three alternate translation start sites (1). Egr-1 has also been reported to be …

We have previously described two cellular immediate-early genes, Egr-1 (mouse) and
EGR2 (human) that encode zinc finger proteins. Here we report the characterization of a …

The transcription factor Egr-1 regulates the expression of numerous genes involved in
differentiation, growth, and in response to environmental signals. Egr-1 activity is modulated …

Early growth response-1 (Egr-1) is a Cys2-His2-type zinc-finger transcription factor. A broad
range of extracellular stimuli is capable of activating Egr-1, thus mediating growth …

Egr-1 is an immediate-early response gene induced by diverse signals that initiate growth
and differentiation. Its cDNA sequence predicts a protein with zinc fingers. We have …