Abstract Inv (16)(p13q22) and t (16; 16)(p13; q22) are cytogenetic hallmarks of acute
myelomonoblastic leukaemia, most of them associated with abnormal bone marrow …

The pericentric inversion of chromosome 16 (inv (16)(p12q22)) is a characteristic karyotypic
abnormality associated with acute myeloid leukemia, most commonly of the M4Eo subtype. It …

Acute myeloid leukemia (AML) with an inv (16)(p13q22) or t (16; 16)(p13; q22) chromosomal
abnormality represents one of the most common subtypes of de novo cases. These …

Inv (16)(p13; q22) or t (16; 16)(p13; q22) is one of the most frequent recurring chromosomal
rearrangements detected in AML, generally observed in cases showing myelo-monocytic …

The inv (16)(p13q22) is observed in 16% of patients with acute myelogenous leukemia
(AML). It is classically found in the AML M4Eo subtype, which has distinctive morphological …

We present a case of acute myeloid leukemia (AML) with a cytogenetically typical inv
(16)(p13q22), M4 morphology and eosinophilia. However, studies revealed a CBFβ-MYH11 …

Acute myelomonocytic leukemia with bone marrow eosinophilia (AML M4Eo) is a subtype of
AML with distinct morphological features. Inversion (16)(p13. 1q22), t (16; 16)(p13. 1; q22) …

Inv (16)(p13q22) and the related translocation t (16; 16)(p13; q22) generate a CBFB-MYH11
fusion gene transcript and are commonly found in acute myeloid leukemia (AML) M4Eo. 1 …

The spectrum of CBFB-MYH11 fusion transcripts in acute myeloid leukemia (AML) M4eo
with inv (16)/t (16; 16) is heterogeneous. Approximately 85% show type A CBFB-MYH11 …

Acute myeloid leukemia (AML) cases with inv (16)(p13q22) or t (16; 16)(p13; q22) are
characterized by multiple CBFB-MYH11 fusion transcripts, type A being the most frequent …