[HTML][HTML] Circulating tumor cells from enumeration to analysis: Current challenges and future opportunities

YP Yang, TM Giret, RJ Cote - Cancers, 2021 - mdpi.com
Simple Summary With estimated numbers of 1–10 per mL of blood, circulating tumor cells
(CTCs) are extremely rare compared to white (a few million) or red (billions) blood cells …

Molecular characterization of circulating tumor cells—from bench to bedside

Y Li, S Wu, F Bai - Seminars in Cell & Developmental Biology, 2018 - Elsevier
Circulating tumor cells (CTCs) are cancer cells discovered in cancer patients' peripheral
blood that successfully escape from the primary tumor site and/or metastases, struggle to …

Circulating tumor cells: utopia or reality?

V Conteduca, R Zamarchi, E Rossi, V Condelli… - Future …, 2013 - Taylor & Francis
Circulating tumor cells (CTCs) could be considered a sign of tumor aggressiveness, but
highly sensitive and specific methods of CTC detection are necessary owing to the rarity and …

[HTML][HTML] Detection of circulating tumor cells: opportunities and challenges

S Ju, C Chen, J Zhang, L Xu, X Zhang, Z Li, Y Chen… - Biomarker …, 2022 - Springer
Circulating tumor cells (CTCs) are cells that shed from a primary tumor and travel through
the bloodstream. Studying the functional and molecular characteristics of CTCs may provide …

[HTML][HTML] Circulating tumor cells, enumeration and beyond

JM Hou, M Krebs, T Ward, K Morris, R Sloane… - Cancers, 2010 - mdpi.com
The detection and enumeration of circulating tumor cells (CTCs) has shown significant
clinical utility with respect to prognosis in breast, colorectal and prostate cancers. Emerging …

[HTML][HTML] Current approaches for avoiding the limitations of circulating tumor cells detection methods—implications for diagnosis and treatment of patients with solid …

A Kowalik, M Kowalewska, S Góźdź - Translational Research, 2017 - Elsevier
Eight million people die of cancer each year and 90% of deaths are caused by systemic
disease. Circulating tumor cells (CTCs) contribute to the formation of metastases and thus …

Circulating tumor cells: a window into cancer biology and metastasis

S Maheswaran, DA Haber - Current opinion in genetics & development, 2010 - Elsevier
The presence of circulating tumor cells (CTCs) accompanies tumor invasion into the
bloodstream. Detection, monitoring, and molecular analysis of these rare cancer cells shed …

Circulating tumor cells: strategies for capture, analyses, and propagation

A Agarwal, M Balic, D El-Ashry, RJ Cote - The Cancer Journal, 2018 - journals.lww.com
Circulating tumor cells (CTCs) play a central role in tumor dissemination and metastases,
which are ultimately responsible for most cancer deaths. Technologies that allow for …

Circulating tumor cells: detection, molecular profiling and future prospects

K Jacob, C Sollier, N Jabado - Expert review of proteomics, 2007 - Taylor & Francis
Disseminated malignancy is responsible for the vast majority of cancer-related deaths.
During this process, circulating tumor cells (CTC) are generated, spread from the primary …

Circulating tumor cells: State-of-the-art update on technologies and clinical applications

K Yap, EN Cohen, JM Reuben, JD Khoury - Current hematologic …, 2019 - Springer
Abstract Purpose of Review Circulating tumor cells represent rare events in the peripheral
blood of patients with cancer that can provide insight into tumor biology. CTC enumeration …