Role of alcohol oxidative metabolism in its cardiovascular and autonomic effects

MM El-Mas, AA Abdel-Rahman - … to Human Health and Precision Medicine, 2019 - Springer
Several review articles have been published on the neurobehavioral actions of
acetaldehyde and other ethanol metabolites as well as in major alcohol-related disorders …

Combined Catalase and ADH Inhibition Ameliorates Ethanol‐Induced Myocardial Dysfunction Despite Causing Oxidative Stress in Conscious Female Rats

F Yao, AA Abdel‐Rahman - Alcoholism: Clinical and …, 2017 - Wiley Online Library
Background Ethanol (EtOH)‐evoked oxidative stress, which contributes to myocardial
dysfunction in proestrus rats, is mediated by increases in NADPH oxidase (Nox) activity …

Low vs. high alcohol: central benefits vs. detriments

Y Tizabi, B Getachew, CL Ferguson, AB Csoka… - Neurotoxicity …, 2018 - Springer
The dose-dependent effects of alcohol, where the initial euphoric and stimulant effects
initiated by the exposure to low ethanol levels can quickly lead to a deadly consequence are …

Alcohol effects on cardiac function

JD Gardner, AJ Mouton - Comprehensive Physiology, 2011 - Wiley Online Library
The consumption of ethanol can have both beneficial and detrimental effects on the function
of the heart and cardiovascular system, depending on the amount consumed. Low‐to …

[HTML][HTML] Alcohol's effects on the cardiovascular system

MR Piano - Alcohol research: current reviews, 2017 - ncbi.nlm.nih.gov
Alcohol use has complex effects on cardiovascular (CV) health. The associations between
drinking and CV diseases such as hypertension, coronary heart disease, stroke, peripheral …

Mechanisms of alcoholic heart disease

J Ren, LE Wold - Therapeutic advances in cardiovascular …, 2008 - journals.sagepub.com
Compromised heart function is regularly seen in patients with chronic alcohol ingestion and
is often manifested as cardiomegaly, reduced myocardial contractility (with concomitant …

Alcohol in moderation, cardioprotection, and neuroprotection: epidemiological considerations and mechanistic studies

MA Collins, EJ Neafsey, KJ Mukamal… - Alcoholism: clinical …, 2009 - Wiley Online Library
In contrast to many years of important research and clinical attention to the pathological
effects of alcohol (ethanol) abuse, the past several decades have seen the publication of a …

Reactive oxygen species are central mediators of vascular dysfunction and hypertension induced by ethanol consumption

JC Padovan, TMH Dourado, GF Pimenta… - Antioxidants, 2023 - mdpi.com
Consumption of high amounts of ethanol is a risk factor for development of cardiovascular
diseases such as arterial hypertension. The hypertensive state induced by ethanol is a …

Oxidative stress and autonomic dysregulation contribute to the acute time‐dependent myocardial depressant effect of ethanol in conscious female rats

BM Ibrahim, M Fan… - Alcoholism: Clinical and …, 2014 - Wiley Online Library
Background The molecular mechanisms of the acute hypotensive and indirectly assessed
cardiac depressant effect of ethanol (E t OH)‐evoked myocardial depression and …

Role of acetaldehyde in the actions of ethanol on the brain—a review

WA Hunt - Alcohol, 1996 - Elsevier
Over the last 30 years, acetaldehyde has been postulated to mediate various actions of
ethanol on the brain. Experiments have studied ethanol consumption after acetaldehyde …