Effects of bezafibrate on insulin secretion and peripheral insulin sensitivity in hyperlipidemic patients with and without diabetes

G Riccardi, S Genovese, G Saldalamacchia, L Patti… - Atherosclerosis, 1989 - Elsevier
Although it has been reported that bezafibrate influences carbohydrate metabolism, this
possibility has never been properly evaluated in a controlled clinical trial. In this study we …

Double‐blind Placebo‐controlled Study of the Effects of Bezafibrate on Blood Lipids, Lipoproteins, and Fibrinogen in Hyperlipidaemic Type 1 Diabetes Mellitus

PH Winocour, PN Durrington, D Bhatnagar… - Diabetic …, 1990 - Wiley Online Library
The effects of bezafibrate 400 mg day− 1 or placebo administered for 3 months, were
compared in 36 patients with stable Type 1 diabetes and hypercholesterolaemia and/or …

Effects of bezafibrate on insulin sensitivity and glucose tolerance in subjects with combined hyperlipidemia

P Karhapää, M Uusitupa, E Voutilainen… - Clinical …, 1992 - Wiley Online Library
To investigate whether the lowering of triglyceride levels has beneficial effects on glucose
metabolism, we studied 13 nondiabetic men with combined hyperlipidemia (phenotype IIB) …

Effects of slow release bezafibrate on the lipid pattern and on blood glucose of type 2 diabetic patients with hyperlipidaemia

A Rovellini, D Sommariva, A Branchi, F Maraffi… - Pharmacological …, 1992 - Elsevier
Ninety-eight type 2 diabetic patients with hyperlipidaemia in stable metabolic control with
diet alone (41) or diet plus hypoglycaemic agents (57) were divided into two groups: group 1 …

Effect of bezafibrate on metabolic profiles in non-insulin-dependent diabetes mellitus

K Alberti, R Jones, MF Laker, ABM Swai… - Journal of …, 1990 - journals.lww.com
Non-insuiin-dependent diabetes mellitus (NIDDM) is characterized by hyperglycemia
secondary to increased hepatic glucose output and impaired extrahepatic insulin sensitivity …

Effects of bezafibrate on lipid and glucose metabolism in dyslipidemic patients with diabetes: the J-BENEFIT study

T Teramoto, K Shirai, H Daida, N Yamada - Cardiovascular diabetology, 2012 - Springer
Background The hypoglycemic effect of bezafibrate is well established, but administration to
a large population of patients with diabetes has not been reported. We investigated glycemic …

Bezafibrate affects lipid, lipo-and apolipoprotein pattern in non-insulin-dependent diabetic patients

G Niort, R Gambino, M Cassader… - … and metabolic research, 1993 - thieme-connect.com
To assess bezafibrate efficacy in a diabetic population a single-blind randomized study was
performed in 32 diet-resistant type IIb hyperlipidaemic non-insulin-dependent (NID) diabetic …

Bezafibrate reduces blood glucose in type 2 diabetes mellitus

S Ogawa, K Takeuchi, K Sugimura, M Fukuda, R Lee… - Metabolism, 2000 - Elsevier
The clinical efficacy of bezafibrate was examined with special reference to glucose
metabolism in patients with type 2 diabetes mellitus (DM2). In protocol 1, 342 patients with …

Improvement of glucose tolerance by bezafibrate in non-obese patients with hyperlipidemia and impaired glucose tolerance

I Inoue, K Takahashi, S Katayama, S Akabane… - Diabetes research and …, 1994 - Elsevier
Glucose intolerance or diabetes mellitus, hyperlipidemia, obesity and hypertension may
have a close interrelation based on insulin resistance. We selected 28 impaired glucose …

Bezafibrate improves hypertension and insulin sensitivity in humans

JI Kim, T Tsujino, Y Fujioka, K Saito… - Hypertension …, 2003 - jstage.jst.go.jp
We examined cellular membrane fatty acid composition and insulin sensitivity in patients
with mild essential hypertension and hyperlipidemia, and investigated whether bezafibrate …