We review the substantial recent progress made in understanding the underlying
mechanisms controlling breathing and the applicability of these findings to selected human …

Unstable periodic breathing with intermittent ventilatory overshoots and undershoots
commonly occurs in chronic heart failure, in hypoxia, with chronic opioid use and in certain …

In humans respiratory chemoreceptors are located centrally in the medulla (Nattie, 2010)
and peripherally in the carotid bodies (Torrance, 1996; Kumar & Bin-Jaliah, 2007). Does the …

Substantial advances have been made recently into the discovery of fundamental
mechanisms underlying the neural control of breathing and even some inroads into …

In health, and during the course of many diseases, the ventilatory control system protects not
only the adequacy of overall alveolar ventilation but also the stability of ventilatory rhythm …

The mathematical model of the respiratory control system described in a previous
companion paper is used to analyse the ventilatory response to hypoxic stimuli. Simulation …

This work presents a mathematical model of the human respiratory control system, based on
physiological knowledge. It includes three compartments for gas storage and exchange …

Obstructive sleep disorders develop when the normal reduction in pharyngeal dilator activity
at sleep onset occurs in an individual whose pharynx requires a relatively high level of …

Although many excitatory and inhibitory neural inputs from central and peripheral sources
including the chemoreceptors have been discovered, the elements essential for setting the …

Breathing occurs in single breaths and in patterns which are altered by the onset,
progression and resolution of respiratory diseases. Through modulations of rate, depth, and …