Clinical data supporting the best therapeutic approach in leptomeningeal disease (LMD;
also known as leptomeningeal metastases or leptomeningeal carcinomatosis) are lacking …

Leptomeningeal metastasis (LM) in breast cancer patients confers a uniformly poor
prognosis and decreased quality of life. Treatment options are limited and often ineffective …

Leptomeningeal metastasis (LM), which occurs when malignant cells spread to the central
nervous system, is becoming an increasingly common complication in patients with breast …

New strategies for the treatment of breast cancer with lepto... : Current Opinion in Oncology
New strategies for the treatment of breast cancer with leptomeningeal metastasis : Current …

Purpose Leptomeningeal disease (LMD) is an advanced metastatic disease presentation
portending a poor prognosis with minimal treatment options. The advent and widespread …

Background Breast cancer (BC) is one of the solid tumors most commonly associated with
leptomeningeal disease (LMD). LMD carries a devastating prognosis; however, disease …

Background There is limited data on the impact of specific patient characteristics, tumor
subtypes or treatment interventions on survival in breast cancer LM. Methods A systematic …

Background Leptomeningeal metastasis (LM) is one of the major problems in the
management of metastatic breast cancer; typically, LM has a devastating prognosis and …

Purpose Leptomeningeal disease (LMD) is an uncommon complication of advanced breast
cancer. The prognosis is poor, and although radiotherapy (RT), systemic and intra-thecal (IT) …

Purpose Leptomeningeal disease is a rare presentation of advanced metastatic breast
cancer. The purpose of this study was to evaluate craniospinal progression between …