The rapid rise of obesity, type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD)
during the last few decades among South Asians has been largely attributed to a major shift …

Background—Several consortia have pursued genome-wide association studies for
identifying novel genetic loci for blood pressure, lipids, hypertension, etc. They …

Obesity is associated with environmental factors; however, information about gene–
environment interactions is lacking. We aimed to elucidate the effects of gene–environment …

Background The genetic contribution to complex diseases or traits, including cardio-
metabolic traits, has been elucidated recently by large-scale genome-wide association …

Background Both genetic and nongenetic factors can predispose individuals to
cardiovascular risk. Finding ways to alter these predispositions is important for …

The relationship between lifestyles and cardiometabolic outcomes varies between
individuals. In 382,275 UK Biobank Europeans, we investigate how lifestyles interact with …

Several studies on gene–diet interactions (nutrigenetics) have been performed in western
populations; however, there are only a few studies to date in lower middle-income countries …

Background and aims Cardiometabolic disorders (CMD) arise from a constellation of
features such as increased adiposity, hyperlipidemia, hypertension and compromised …

Introduction The prevalence of cardiometabolic diseases has increased in Latin American
and the Caribbean populations (LACP). To identify gene-lifestyle interactions that modify the …

Identifying gene-environment interactions that affect cardiovascular disease or associated
cardiometabolic diseases may identify novel pathways of cardiovascular disease …