Although it is now becoming more evident that the strain of mouse used to generate
genetically modified models for the study of endocrine disorders contributes to the ensuing …

Aims/hypothesis Metabolic disorders are commonly investigated using knockout and
transgenic mouse models. A variety of mouse strains have been used for this purpose …

We have previously shown that C57BL/6J (B6) mice develop severe obesity and diabetes if
weaned onto high-fat diets, whereas A/J mice tend to be obesity and diabetes-resistant. The …

Mouse populations differing in metabolic rate have been developed through selection for
high (MH) and low (ML) heat loss (HLOSS), along with randomly selected controls (MC) …

The increasing production of genetically-modified mouse models has necessitated studies
to determine the inherent physiological characteristics of commonly used mouse strains. In …

The strain distribution for macronutrient diet selection was described in 13 mouse strains
(AKR/J, NZB/B1NJ, C57BL/6J, C57BL/6ByJ, DBA/2J, SPRET/Ei, CD-1, SJL/J, SWR/J, 129/J …

Cheverud, James M., L. Susan Pletscher, Ty T. Vaughn, and Bess Marshall. Differential
response to dietary fat in large (LG/J) and small (SM/J) inbred mouse strains. Physiol …

C57BL/6J mice were fed a high-fat, carbohydrate-free diet (HFD) for 9 mo. Approximately
50% of the mice became obese and diabetic (ObD),∼ 10% lean and diabetic (LD),∼ 10 …

Mouse models are widely used for elucidating mechanisms underlying type 2 diabetes.
Genetic background profoundly affects metabolic phenotype; therefore selecting the …

Objective: The aim of this study was to assess the suitability of A/J and C57BL/6J mice of
both sexes as models of some components of the human metabolic syndrome (MetS) under …