Increased cellular infiltrate in inflammatory synovia of osteoarthritic knees

I Saito, T Koshino, K Nakashima, M Uesugi… - Osteoarthritis and …, 2002 - Elsevier
Objective To determine the nature and origin of synovial inflammation in knees with
osteoarthritis (OA). Method Synovial samples were obtained from 21 medial compartmental …

[PDF][PDF] Synovial inflammation in patients with different stages of knee osteoarthritis

R Ene, RD Sinescu, P Ene, MM Cîrstoiu… - Rom J Morphol …, 2015 - academia.edu
The synovium is an intra-articular mesenchymal tissue and essential for the normal joint
function. It is involved in many pathological characteristic processes and sometimes specific …

Synovial tissue inflammation in early and late osteoarthritis

MJ Benito, DJ Veale, O FitzGerald… - Annals of the …, 2005 - ard.bmj.com
Objective: To compare selected immunohistological features of inflammation in synovial
tissue from patients with early and late osteoarthritis (OA). Methods: Synovial tissue samples …

Microarchitecture and protective mechanisms in synovial tissue from clinically and arthroscopically normal knee joints

MD Smith, E Barg, H Weedon, V Papengelis… - Annals of the …, 2003 - ard.bmj.com
Background: Synovial biopsies are used to study synovial immunopathology and are
increasingly applied for the evaluation of new therapeutic strategies in chronic arthritis …

Macroscopic and microscopic features of synovial membrane inflammation in the osteoarthritic knee: correlating magnetic resonance imaging findings with disease …

D Loeuille, I Chary‐Valckenaere… - Arthritis & …, 2005 - Wiley Online Library
Objective To determine the magnetic resonance imaging (MRI), macroscopic, and
microscopic characteristics of synovial membrane inflammation, to study the relationship …

Immunohistochemistry of normal human knee synovium: a quantitative study

JA Singh, T Arayssi, P Duray… - Annals of the rheumatic …, 2004 - ard.bmj.com
Objective: To describe the immunohistochemical characteristics of knee synovium from
normal healthy subjects. Methods: 12 healthy subjects underwent needle biopsy of knee …

[HTML][HTML] Synovial inflammation, immune cells and their cytokines in osteoarthritis: a review

BJE De Lange-Brokaar, A Ioan-Facsinay… - Osteoarthritis and …, 2012 - Elsevier
OBJECTIVE: Although osteoarthritis (OA) is considered a non-inflammatory condition, it is
widely accepted that synovial inflammation is a feature of OA. However, the role of immune …

Inflammatory cells in patients with endstage knee osteoarthritis: a comparison between the synovium and the infrapatellar fat pad

IR Klein-Wieringa, BJE de Lange-Brokaar… - The Journal of …, 2016 - jrheum.org
Objective. To get a better understanding of inflammatory pathways active in the osteoarthritic
(OA) joint, we characterized and compared inflammatory cells in the synovium and the …

From osteoarthritic synovium to synovial-derived cells characterization: synovial macrophages are key effector cells

C Manferdini, F Paolella, E Gabusi, Y Silvestri… - Arthritis research & …, 2016 - Springer
Background The aim of the study was to characterize synovial cells from OA synovium with
low-grade and moderate-grade synovitis and to define the role of synovial macrophages in …

[PDF][PDF] Human knee synovial fluid cytokines correlated with grade of knee osteoarthritis

CT Vangsness Jr, WS Burke… - Bulletin of the NYU …, 2011 - researchgate.net
The purpose of this pilot study was to evaluate the cytokine profile of human knee synovial
fluid and correlate this with the subject's degree of articular cartilage degradation …