The kynurenine pathway of tryptophan metabolism has been involved in ADHD We
quantified basal levels and daily fluctuations of tryptophan and several kynurenine …

This study aims at determining serum levels of tryptophan and other metabolites of the
kynurenine pathway in children with attention deficit hyperactivity disorder (ADHD) …

Background The essential amino acid tryptophan is catabolised mainly through the
kynurenine pathway. Altered circulating levels of kynurenines have been reported in chronic …

Preliminary evidence shows that the kynurenine pathway (KP) may be altered in attention-
deficit/hyperactivity disorder (ADHD). We thus conducted a systematic review and meta …

To address the heterogeneous nature of adolescent major depression (MDD), we
investigated anhedonia, a core symptom of MDD. We recently reported activation of the …

Accumulating data presented that tryptophan metabolic pathway (TMP) may play a role in
attention-deficit/hyperactivity disorder (ADHD). However, no study have investigated …

Background: Although adolescent major depressive disorder (MDD) is acknowledged to be
a heterogeneous disorder, no studies have reported on biological correlates of its clinical …

BACKGROUND: Cytokine induction of the enzyme indoleamine 2, 3-dioxygenase (IDO) has
been implicated in the development of major depressive disorder (MDD). IDO metabolizes …

Objectives Kynurenine, kynurenic and quinolinic acid are important metabolites in
tryptophan metabolism. Due to an involvement in glutamatergic neurotransmission and …

Objective Increased plasma kynurenine has been reported in tic disorder patients, and this
observation has been suggested to be indicative of immune dysregulation. In the present …