Osteoporotic fracture healing is an orthopaedic challenge due to excessive bone resorption
and impaired osteogenesis. Majority of current treatment strategies focus on regulating bone …

Fabrication of osteoconductive scaffold with osteoinductive capability and appropriate
resorption rate is of great significance for treating bone defects. To achieve this aim …

The development of bone replacement materials is an important objective in the field of
orthopaedic surgery. Due to the drawbacks of treating bone defects with autografts, synthetic …

Bone defects in load bearing areas require bone reconstruction with strong biomaterial
having mechanical characteristics like cortical bone. Bioceramics are biomaterials that …

Osteoporotic bone defect repair using synthetic biomaterial-based strategies is promising
but remains challenging as it requires superior efficient osteogenic effects. Due to the strong …

The use of porous three-dimensional (3D) bioceramic scaffolds to facilitate the regeneration
of bone defects has attracted great attention because their structures closely mimic the …

Aim: To compare the effect of bovine bone derived porous hydroxyapatite (BDHA) scaffold
on proliferation and osteogenic differentiation of human bone marrow-derived mesenchymal …

Drug functionalized scaffolds are currently being employed to improve local delivery of
osteoprotective drugs with the aim of reducing their loading dose as well as unwanted …

In this study a novel nano-structured hydroxyapatite (HA) incorporated with different fractions
of Sr2+ and SO42− ions has been synthesized using the wet precipitation method and …

Injectable nanoscale hydroxyapatite (nHA) systems are highly promising biomaterials to
address clinical needs in bone tissue regeneration, due to their excellent biocompatibility …