Cytokines, Signaling Pathways, and Effector Molecules Required for the Control of Leishmania (Viannia) braziliensis in Mice
FJS Rocha, U Schleicher, J Mattner, G Alber… - Infection and …, 2007 - Am Soc Microbiol
Cutaneous leishmaniasis is caused by protozoan parasites of the genus Leishmania. The
mechanisms of pathogen control have been established primarily in the mouse model of …
mechanisms of pathogen control have been established primarily in the mouse model of …
Murine model of chronic L. (Viannia) panamensis infection: Role of IL‐13 in disease
TM Castilho, K Goldsmith‐Pestana… - European journal of …, 2010 - Wiley Online Library
Leishmania (Viannia) organisms are the most prevalent etiologic agents of human
cutaneous leishmaniasis in the Americas. Nevertheless, our knowledge of the …
cutaneous leishmaniasis in the Americas. Nevertheless, our knowledge of the …
BALB/c Mice Infected with Antimony Treatment Refractory Isolate of Leishmania braziliensis Present Severe Lesions due to IL-4 Production
Background Leishmania braziliensis is the main causative agent of cutaneous leishmaniasis
in Brazil. Protection against infection is related to development of Th1 responses, but the …
in Brazil. Protection against infection is related to development of Th1 responses, but the …
Impaired Expression of Inflammatory Cytokines and Chemokines at Early Stages of Infection with Leishmania amazonensis
Infection of mice with Leishmania major results in disease progression or resolution, largely
depending on the genetic backgrounds of the mouse strains. Infection with Leishmania …
depending on the genetic backgrounds of the mouse strains. Infection with Leishmania …
Control of New World cutaneous leishmaniasis is IL‐12 independent but STAT4 dependent
LU Buxbaum, JE Uzonna… - European journal of …, 2002 - Wiley Online Library
Abstract Leishmania mexicana, a New World protozoan parasite, induces small, chronic, but
non‐progressive lesions in C57BL/6 (B6) mice. In this study we investigated the role of IL …
non‐progressive lesions in C57BL/6 (B6) mice. In this study we investigated the role of IL …
A recombinant Leishmania antigen that stimulates human peripheral blood mononuclear cells to express a Th1-type cytokine profile and to produce interleukin 12.
YA Skeiky, JA Guderian, DR Benson… - The Journal of …, 1995 - rupress.org
Leishmania braziliensis causes cutaneous and mucosal leishmaniasis in humans. Most
patients with cutaneous leishmaniasis heal spontaneously and may therefore have …
patients with cutaneous leishmaniasis heal spontaneously and may therefore have …
Immunopathogenesis of infection with the visceralizing Leishmania species
ME Wilson, SMB Jeronimo, RD Pearson - Microbial pathogenesis, 2005 - Elsevier
Human leishmaniasis is a spectral disease that includes asymptomatic self-resolving
infection, localized skin lesions, and progressive visceral leishmaniasis. With some overlap …
infection, localized skin lesions, and progressive visceral leishmaniasis. With some overlap …
IL-10 and TGF-β control the establishment of persistent and transmissible infections produced by Leishmania tropica in C57BL/6 mice
CF Anderson, R Lira, S Kamhawi, Y Belkaid… - The journal of …, 2008 - journals.aai.org
Leishmania tropica is the causative agent of Old World anthroponotic cutaneous
leishmaniasis, which is characterized by lesions that take an extended period of time to heal …
leishmaniasis, which is characterized by lesions that take an extended period of time to heal …
Subversion and Utilization of Host Innate Defense by Leishmania amazonensis
L Soong - Frontiers in immunology, 2012 - frontiersin.org
Infection with Leishmania amazonensis and other members of the Leishmania mexicana
complex can lead to diverse clinical manifestations, some of which are relatively difficult to …
complex can lead to diverse clinical manifestations, some of which are relatively difficult to …
Resolution of an infection with Leishmania braziliensis confers complete protection to a subsequent challenge with Leishmania major in BALB/c mice
HC Lima, GK DeKrey, RG Titus - Memórias do Instituto Oswaldo Cruz, 1999 - SciELO Brasil
Both Leishmania major and L. braziliensis induce cutaneous leishmaniasis in BALB/c mice.
Whereas BALB/c mice die of infection with L. major, they cure an infection with L …
Whereas BALB/c mice die of infection with L. major, they cure an infection with L …