Injectable porous nano-hydroxyapatite/chitosan/tripolyphosphate scaffolds with improved compressive strength for bone regeneration

SP Uswatta, IU Okeke, AC Jayasuriya - Materials Science and Engineering …, 2016 - Elsevier
In this study we have fabricated porous injectable spherical scaffolds using chitosan
biopolymer, sodium tripolyphosphate (TPP) and nano-hydroxyapatite (nHA). TPP was …

Fabrication and in vitro biocompatibility of sodium tripolyphosphate-crosslinked chitosan–hydroxyapatite scaffolds for bone regeneration

CY Goh, SS Lim, KY Tshai, AWZZ El Azab… - Journal of Materials …, 2019 - Springer
The aims of this study were to fabricate a novel chitosan–hydroxyapatite (CHA) scaffold
crosslinked with sodium tripolyphosphate (TPP) and evaluate its in vitro biocompatibility …

Chitosan/hydroxyapatite hybrid scaffold for bone tissue engineering

V Brun, C Guillaume, S Mechiche Alami… - Bio-medical …, 2014 - content.iospress.com
BACKGROUND: To favor regeneration following critical bone defect, a combination of
autologous bone graft and biomaterials is currently used. Major drawbacks of such …

[HTML][HTML] Preparation and characterization of homogeneous hydroxyapatite/chitosan composite scaffolds via in-situ hydration

H Li, CR Zhou, MY Zhu, JH Tian, JH Rong - Journal of Biomaterials and …, 2010 - scirp.org
Hydroxyapatite (HAP)/Chitosan (CS) composite is a biocompatible and bioactive material for
tissue engineering. A novel homogeneous HAP/CS composite scaffold was developed via …

Preparation and characterization of nano-sized hydroxyapatite/alginate/chitosan composite scaffolds for bone tissue engineering

HL Kim, GY Jung, JH Yoon, JS Han, YJ Park… - Materials Science and …, 2015 - Elsevier
The aim of this study was to develop chitosan composite scaffolds with high strength and
controlled pore structures by homogenously dispersed nano-sized hydroxyapatite (nano …

Preparation and properties of a highly dispersed nano-hydroxyapatite colloid used as a reinforcing filler for chitosan

R Ying, H Wang, R Sun, K Chen - Materials Science and Engineering: C, 2020 - Elsevier
Abstract Hydroxyapatite/chitosan (HAp/CS) composites have been widely studied and
applied in tissue engineering fields due to their excellent biocompatibility and degradability …

In vivo evaluation of porous hydroxyapatite/chitosan–alginate composite scaffolds for bone tissue engineering

HH Jin, DH Kim, TW Kim, KK Shin, JS Jung… - International journal of …, 2012 - Elsevier
Porous hydroxyapatite (HAp)/chitosan–alginate composite scaffolds were prepared through
in situ co-precipitation and freeze-drying for bone tissue engineering. The composite …

Design and characterization of a novel chitosan/nanocrystalline calcium phosphate composite scaffold for bone regeneration

BM Chesnutt, AM Viano, Y Yuan, Y Yang… - … Research Part A: An …, 2009 - Wiley Online Library
To meet the challenge of regenerating bone lost to disease or trauma, biodegradable
scaffolds are being investigated as a way to regenerate bone without the need for an auto …

Growth of osteoblast‐like cells on biomimetic apatite‐coated chitosan scaffolds

I Manjubala, I Ponomarev, I Wilke… - Journal of Biomedical …, 2008 - Wiley Online Library
Porous scaffold materials that can provide a framework for the cells to adhere, proliferate,
and create extracellular matrix are considered to be suitable materials for bone …

A porous scaffold from bone-like powder loaded in a collagen–chitosan matrix

K Cui, Y Zhu, XH Wang, QL Feng… - Journal of bioactive and …, 2004 - journals.sagepub.com
Porous scaffolds that mimic both the structure and composition of natural bone were
prepared. Nano-hydroxyapatite particles were first synthesized through deposition of …