G protein-coupled adenosine (P1) and P2Y receptors: ligand design and receptor interactions
KA Jacobson, R Balasubramanian, F Deflorian… - Purinergic …, 2012 - Springer
The medicinal chemistry and pharmacology of the four subtypes of adenosine receptors
(ARs) and the eight subtypes of P2Y receptors (P2YRs, activated by a range of purine and …
(ARs) and the eight subtypes of P2Y receptors (P2YRs, activated by a range of purine and …
Purine and pyrimidine receptors
G Burnstock - Cellular and molecular life sciences, 2007 - Springer
Adenosine 5′-triphosphate (ATP), in addition to its intracellular roles, acts as an
extracellular signalling molecule via a rich array of receptors, which have been cloned and …
extracellular signalling molecule via a rich array of receptors, which have been cloned and …
Adenosine (P1) receptor signalling
BB Fredholm, G Arslan, B Kull, E Kontny… - Drug development …, 1996 - Wiley Online Library
The coupling of the four defined types of adenosine receptors to G proteins and the
consequent activation of effector pathways is briefly summarized. It is pointed out that the G …
consequent activation of effector pathways is briefly summarized. It is pointed out that the G …
Agonists and antagonists for purinergic receptors
Membrane receptors that are activated by the purine nucleoside adenosine (adenosine
receptors) or by purine or pyrimidine nucleotides (P2Y and P2X receptors) transduce …
receptors) or by purine or pyrimidine nucleotides (P2Y and P2X receptors) transduce …
Medicinal chemistry of adenosine, P2Y and P2X receptors
KA Jacobson, CE Müller - Neuropharmacology, 2016 - Elsevier
Pharmacological tool compounds are now available to define action at the adenosine (ARs),
P2Y and P2X receptors. We present a selection of the most commonly used agents to study …
P2Y and P2X receptors. We present a selection of the most commonly used agents to study …
Functions of heteromeric association between adenosine and P2Y receptors
H Nakata, K Yoshioka, T Kamiya, H Tsuga… - Journal of molecular …, 2005 - Springer
It is now well accepted that G protein-coupled receptors (GPCRs) can be directly associated,
as either homo-or hetero-oligomers, to alter their functions. G protein-coupled purinergic …
as either homo-or hetero-oligomers, to alter their functions. G protein-coupled purinergic …
[引用][C] Release, metabolism and interconversion of adenine and uridine nucleotides: implications for G protein-coupled P2 receptor agonist selectivity
TK Harden, ER Lazarowski, RC Boucher - Trends in Pharmacological …, 1997 - Elsevier
The occurrence of a physiologically relevant release of adenine nucleotides that results in
the activation of cell surface receptors was formally postulated several decades ago',?. More …
the activation of cell surface receptors was formally postulated several decades ago',?. More …
Heteromeric association creates a P2Y-like adenosine receptor
K Yoshioka, O Saitoh, H Nakata - Proceedings of the …, 2001 - National Acad Sciences
Adenosine and its endogenous precursor ATP are main components of the purinergic
system that modulates cellular and tissue functions via specific adenosine and ATP …
system that modulates cellular and tissue functions via specific adenosine and ATP …
[HTML][HTML] Hetero-oligomerization of adenosine A1 receptors with P2Y1 receptors in rat brains
K Yoshioka, R Hosoda, Y Kuroda, H Nakata - FEBS letters, 2002 - Elsevier
Adenosine and ATP modulate cellular and tissue functions via specific P1 and P2 receptors,
respectively. Although, in general, adenosine inhibits excitability and ATP functions as an …
respectively. Although, in general, adenosine inhibits excitability and ATP functions as an …