Colorectal cancer (CRC) is commonly known as one of the most prominent reasons for
cancer‐related death in China. Ras homolog enriched in brain (RHEB) and the mammalian …

Aberrant expression of Ras homolog enriched in brain (RHEB) has been observed in a
variety of cancer tissues and is closely associated with clinicopathological features …

We previously found that the small GTPase Rheb regulates the cell‐cycle inhibitor p27KIP1
(p27) in colon cancer cells by a mTORC1‐independent mechanism. However, the biological …

Colorectal cancer (CRC) is one of the most common malignancies worldwide. Ribosome
biogenesis regulatory protein homolog (RRS1) is an essential factor involved in ribosome …

MicroRNAs (miRNAs) can function as tumor suppressor or oncogenic genes. The putative
targets of miR-223 include tumor suppressor gene, RhoB. Here we sought to investigate the …

Background ERRα, a constitutive transcription factor that regulates energy metabolism,
plays an important role in the progression of various tumours. However, its role in cell …

Ras-like without CAAX1 (RIT1) protein is a member of Ras family, which plays critical roles
in signaling pathways and cellular process regulation. However, the role of RIT1 in …

Background: We previously investigated the mRNA expression of colorectal cancer cell lines
via a microarray analysis and found several genes that were significantly up-regulated by …

Abstract The insulin/Ras Homolog Enriched in Brain (Rheb)/Mammalian Target of
Rapamycin (mTOR) pathway has been implicated in a variety of cancers. The activation of …

This study explores the effect of COL1A2, COL6A3, and THBS2 gene silencing on
proliferation, migration, invasion, and apoptosis of gastric cancer cells through the PI3K‐Akt …