The aim of this study was to determine therapy-related risk factors for the development of
second malignant neoplasm (SMN) after childhood cancer. The German Childhood Cancer …

We report on a nested case–control study with 328 cases with second malignant neoplasm
(SMN) following childhood cancer and 639 matched controls based on the German …

Radiotherapy and chemotherapy are associated with an increased risk of a second
malignant neoplasm (SMN) after a cancer during childhood. This study specified the dose …

During the past several decades, remarkable advances have been achieved in the
treatment and survival of children with cancer. With the increasing population of childhood …

Overall survival from cancer has greatly improved, although it still remains the second
leading cause of mortality in the world. This result was achieved through the use of …

The German Childhood Cancer Registry (GCCR) at the University Medical Centre of the
Johannes Gutenberg University Mainz has been systematically recording all malignant …

Our purpose was to assess the risk of developing a second malignant neoplasm (SMN) after
cancer in childhood and adolescence associated with different treatment modalities. Our …

Background The number of long time survivors of childhood cancer treatment is constantly
increasing over the last decades as a result of advances in diagnosis and treatment. The …

Among a cohort of 981 children who were followed up 4.3–26.5 years after cessation of
antileukemic therapy, eight patients in remission of acute lymphoblastic leukemia (ALL) …

The variation in the risk of solid second malignant neoplasms (SMN) with time since first
cancer during childhood has been previously reported. However, no study has been …