Long non-coding RNAs in the regulation of gene expression: physiology and disease
The identification of RNAs that are not translated into proteins was an important
breakthrough, defining the diversity of molecules involved in eukaryotic regulation of gene …
breakthrough, defining the diversity of molecules involved in eukaryotic regulation of gene …
The how and why of lncRNA function: an innate immune perspective
EK Robinson, S Covarrubias, S Carpenter - Biochimica et Biophysica Acta …, 2020 - Elsevier
Next-generation sequencing has provided a more complete picture of the composition of the
human transcriptome indicating that much of the “blueprint” is a vastness of poorly …
human transcriptome indicating that much of the “blueprint” is a vastness of poorly …
Immunobiology of long noncoding RNAs
MK Atianand, DR Caffrey… - Annual review of …, 2017 - annualreviews.org
The discovery of long noncoding RNAs (lncRNA) has provided a new perspective on gene
regulation in diverse biological contexts. lncRNAs are remarkably versatile molecules that …
regulation in diverse biological contexts. lncRNAs are remarkably versatile molecules that …
Long non-coding RNAs in innate and adaptive immunity
TM Aune, CF Spurlock III - Virus research, 2016 - Elsevier
Long noncoding RNAs (lncRNAs) represent a newly discovered class of regulatory
molecules that impact a variety of biological processes in cells and organ systems. In …
molecules that impact a variety of biological processes in cells and organ systems. In …
Long noncoding RNAs in host–pathogen interactions
F Agliano, VA Rathinam, AE Medvedev, SK Vanaja… - Trends in …, 2019 - cell.com
Long noncoding RNAs (lncRNAs) are key molecules that regulate gene expression in a
variety of organisms. LncRNAs can drive different transcriptional and post-transcriptional …
variety of organisms. LncRNAs can drive different transcriptional and post-transcriptional …
Long noncoding RNAs: insights from biological features and functions to diseases
X Li, Z Wu, X Fu, W Han - Medicinal research reviews, 2013 - Wiley Online Library
Over the past decade, genome‐wide transcriptomic studies have shown that the mammalian
genome is pervasively transcribed and produces many thousands of transcriptomes without …
genome is pervasively transcribed and produces many thousands of transcriptomes without …
Long non-coding RNAs and control of gene expression in the immune system
MK Atianand, KA Fitzgerald - Trends in molecular medicine, 2014 - cell.com
All cells of the immune system rely on a highly integrated and dynamic gene expression
program that is controlled by both transcriptional and post-transcriptional mechanisms …
program that is controlled by both transcriptional and post-transcriptional mechanisms …
Long non-coding RNAs in the regulation of the immune response
JA Heward, MA Lindsay - Trends in immunology, 2014 - cell.com
It is increasingly clear that long non-coding RNAs (lncRNAs) regulate a variety biological
responses, and that they do so by a diverse range of mechanisms. In the field of …
responses, and that they do so by a diverse range of mechanisms. In the field of …
[HTML][HTML] Long non-coding RNAs: Mechanism of action and functional utility
Recent RNA sequencing studies have revealed that most of the human genome is
transcribed, but very little of the total transcriptomes has the ability to encode proteins. Long …
transcribed, but very little of the total transcriptomes has the ability to encode proteins. Long …
Control of immune cell homeostasis and function by lncRNAs
WK Mowel, JJ Kotzin, SJ McCright, VD Neal… - Trends in …, 2018 - cell.com
The immune system is composed of diverse cell types that coordinate responses to infection
and maintain tissue homeostasis. In each of these cells, extracellular cues determine highly …
and maintain tissue homeostasis. In each of these cells, extracellular cues determine highly …