Modulation of VEGF expression in rat bone marrow stromal cells by GDF-5

K Sena, DR Sumner, AS Virdi - Connective tissue research, 2007 - Taylor & Francis
Angiogenesis is essential for bone formation and several bone morphogenetic proteins
(BMPs) have been shown to induce angiogenesis through osteoblast-derived vascular …

Growth and differentiation factor-5 (GDF-5) stimulates osteogenic differentiation and increases vascular endothelial growth factor (VEGF) levels in fat-derived stromal …

Q Zeng, X Li, G Beck, G Balian, FH Shen - Bone, 2007 - Elsevier
Fat-derived adult mesenchymal stem cells can differentiate into different phenotypes
reflecting their potential to regenerate various skeletal tissues. These properties together …

Growth/differentiation factor-5 induces angiogenesisin vivo

H Yamashita, A Shimizu, M Kato, H Nishitoh… - Experimental cell …, 1997 - Elsevier
Bone morphogenetic proteins (BMPs) are multifunctional cytokines, which induce bone and
cartilage formation and exert various other effects on many tissues. Since angiogenesis is …

Vascular endothelial growth factor stimulates chemotactic migration of primary human osteoblasts

U Mayr-Wohlfart, J Waltenberger, H Hausser, S Kessler… - Bone, 2002 - Elsevier
Recent studies have indicated a critical role for vascular endothelial growth factor (VEGF)
during the process of endochondral ossification, in particular in coupling cartilage resorption …

Bone morphogenetic proteins stimulate angiogenesis through osteoblast-derived vascular endothelial growth factor A

MML Deckers, RL Van Bezooijen… - …, 2002 - academic.oup.com
During bone formation and fracture healing there is a cross-talk between endothelial cells
and osteoblasts. We previously showed that vascular endothelial growth factor A (VEGF-A) …

Vascular endothelial growth factor inhibits bone morphogenetic protein 2 expression in rat mesenchymal stem cells

BH Schönmeyr, M Soares, T Avraham… - … Engineering Part A, 2010 - liebertpub.com
Introduction: While several studies report that bone morphogenetic proteins (BMPs) and
vascular endothelial growth factor (VEGF) can act synergistically to improve bone tissue …

BMP2 and VEGF165 transfection to bone marrow stromal stem cells regulate osteogenic potential in vitro

C Zhang, C Meng, D Guan, F Ma - Medicine, 2018 - journals.lww.com
An exogenous supply of bone morphogenetic protein 2 (BMP2) and vascular endothelial
growth factors 165 (VEGF165) will synergize to promote bone regeneration in vivo. The aim …

VEGF improves, whereas sFlt1 inhibits, BMP2‐induced bone formation and bone healing through modulation of angiogenesis

H Peng, A Usas, A Olshanski, AM Ho… - Journal of Bone and …, 2005 - academic.oup.com
We studied the interaction between VEGF and BMP2 during bone formation and bone
healing. Results indicate that VEGF antagonist inhibited BMP2‐elicited bone formation …

VEGF and BMP-6 enhance bone formation mediated by cloned mouse osteoprogenitor cells

F Cui, X Wang, X Liu, AS Dighe, G Balian, Q Cui - Growth factors, 2010 - Taylor & Francis
New strategies such as combined utilization of growth factors may provide a better treatment
for difficult fractures. We have demonstrated enhanced angiogenesis and osteogenesis …

Effects of BMP2 and VEGF165 on the osteogenic differentiation of rat bone marrow‑derived mesenchymal stem cells

Z Lin, JS Wang, L Lin, J Zhang… - Experimental and …, 2014 - spandidos-publications.com
Bone marrow‑derived mesenchymal stem cells (MSCs) are dominant seed cell sources for
bone regeneration. Bone morphogenetic proteins (BMPs) initiate cartilage and bone …