The complex role of T-cell-based immunity in atherosclerosis

P Aukrust, K Otterdal, A Yndestad, WJ Sandberg… - Current atherosclerosis …, 2008 - Springer
Although the pathogenic role of T cells in atherogenesis is well established, the function of
the various T-cell subsets is far from clear. Whereas activation of the T-helper type 1 (Th1) …

Cellular immunity, low-density lipoprotein and atherosclerosis: break of tolerance in the artery wall

DFJ Ketelhuth, GK Hansson - Thrombosis and haemostasis, 2011 - thieme-connect.com
Atherosclerosis is a chronic inflammatory disease. Atherosclerotic plaques contain abundant
immune cells that can dictate and effect inflammatory responses. Among them, T cells are …

Regulatory T-cell immunity in atherosclerosis

Z Mallat, H Ait-Oufella, A Tedgui - Trends in Cardiovascular Medicine, 2007 - Elsevier
Atherosclerosis is an inflammatory disease of the arterial wall where both innate and
adaptive T-cell-driven immunoinflammatory responses contribute to disease development …

T cells in atherogenesis: for better or for worse?

AKL Robertson, GK Hansson - Arteriosclerosis, thrombosis, and …, 2006 - Am Heart Assoc
The idea that atherosclerosis is an inflammatory disease is no longer controversial. Instead,
much of the current research is now focused on understanding what drives this inflammation …

Adaptive immune responses in human atherosclerosis

S Lee, B Bartlett, G Dwivedi - International journal of molecular sciences, 2020 - mdpi.com
Atherosclerosis is a chronic inflammatory disease that is initiated by the deposition and
accumulation of low-density lipoproteins in the artery wall. In this review, we will discuss the …

Immune-inflammatory responses in atherosclerosis: role of an adaptive immunity mainly driven by T and B cells

DA Chistiakov, AN Orekhov, YV Bobryshev - Immunobiology, 2016 - Elsevier
Adaptive immune response plays an important role in atherogenesis. In atherosclerosis, the
proinflammatory immune response driven by Th1 is predominant but the anti-inflammatory …

Adaptive immunity and atherosclerosis

J Andersson, P Libby, GK Hansson - Clinical immunology, 2010 - Elsevier
Atherosclerosis involves the formation of inflammatory arterial lesions and is one of the most
common causes of death globally. It has been evident for more than 20 years that adaptive …

T lymphocyte autoreactivity in inflammatory mechanisms regulating atherosclerosis

E Profumo, B Buttari, L Saso… - The Scientific World …, 2012 - Wiley Online Library
Atherosclerosis has been clearly demonstrated to be a chronic inflammatory disease of the
arterial wall. Both cells of the innate and the acquired immune system, particularly …

Regulatory T‐cell immunity and its relevance to atherosclerosis

S Taleb, A Tedgui, Z Mallat - Journal of internal medicine, 2008 - Wiley Online Library
Atherosclerosis is a chronic inflammatory disease of the arterial wall where both innate and
adaptive immune responses contribute to disease initiation and progression. Recent studies …

T cell subsets and functions in atherosclerosis

R Saigusa, H Winkels, K Ley - Nature Reviews Cardiology, 2020 - nature.com
Atherosclerosis is a chronic inflammatory disease of the arterial wall and the primary
underlying cause of cardiovascular disease. Data from in vivo imaging, cell-lineage tracing …