The purpose of this study was to assess the pharmacokinetic (PK) characteristics, clinical
efficiency, and pharmacoeconomic parameters of piperacillin/tazobactam administered by …

Objective To observe the serum concentration and evaluate clinical efficacy of piperacillin/
tazobactam (TZP) prolonged infusion time in treatment of hospital acquired pneumonia …

Study Objective To determine whether critically ill patients receiving extended‐infusion (EI)
piperacillin/tazobactam would have improved clinical outcomes compared with patients …

Extended infusion of piperacillin/tazobactam over 4 h has been proposed as an alternate
mode of administration to the 30-min intermittent infusion to optimize treatment effects in …

When piperacillin/tazobactam has been used to treat hospitalized patients with serious
infections, including nosocomial pneumonia caused by Pseudomonas aeruginosa, it has …

Study Objective. To compare the effectiveness of extended‐infusion piperacillin‐tazobactam
with that of similar‐spectrum, nonextended‐infusion β‐lactam antibiotics in the treatment of …

While extended infusions of piperacillin-tazobactam (TZP) are increasingly used in practice,
the effect of infusion on the pharmacokinetic (PK) profile of TZP has not been widely …

The objective of this study was to evaluate the steady-state pharmacokinetics and
pharmacodynamics of piperacillin/tazobactam, administered by prolonged infusion, in …

Introduction To enhance the probability of pharmacodynamic target attainment, piperacillin–
tazobactam can be administered as either a continuous or extended-infusion dosage …

Studies evaluating the outcomes of an extended-infusion (EI) piperacillin-tazobactam dosing
strategy in specific cohorts of critically ill patients are lacking. A retrospective, pre …