Biologic therapy for psoriatic arthritis

PJ Mease - Rheumatic Disease Clinics, 2015 - rheumatic.theclinics.com
Biologic therapies are parenteral (administered subcutaneously or intravenously) complex
proteins biologically manufactured in mammalian or yeast cell lines that typically function by …

An evidence-based review of the mechanism of action, efficacy, and safety of biologic therapies in the treatment of psoriasis and psoriatic arthritis

EA Brezinski, AW Armstrong - Current Medicinal Chemistry, 2015 - ingentaconnect.com
Biologic agents have expanded the repertoire of efficacious and safe systemic therapies for
the treatment of moderate-to-severe psoriasis and active psoriatic arthritis. The biologics act …

Psoriatic arthritis: Pathogenesis and novel immunomodulatory approaches to treatment

S Cassell, A Kavanaugh - Journal of immune based therapies and …, 2005 - Springer
Psoriatic arthritis (PsA) is a chronic inflammatory arthropathy characterized by the
association of arthritis and psoriasis. PsA runs a variable course, from mild synovitis to …

[PDF][PDF] A short history of biological therapy for psoriatic arthritis

P Mease - Clin Exp Rheumatol, 2015 - clinexprheumatol.org
Psoriatic arthritis (PsA) is an inflammatory disease characterised by the clinical domains of
arthritis, enthesitis, dactylitis, spondylitis, and psoriasis, often causing significant functional …

Psoriatic arthritis treatment: biological response modifiers

PJ Mease, CE Antoni - Annals of the Rheumatic Diseases, 2005 - ard.bmj.com
In recent years there has been a surge of interest in the treatment of chronic inflammatory
disorders as a result of the development and application of targeted biological therapies …

Evaluation and management of psoriatic arthritis: the role of biologic therapy

EM Ruderman - Journal of the American Academy of Dermatology, 2003 - Elsevier
Clinicians often view psoriatic arthritis (PsA) as a rather minor arthritic disorder because
many are unaware of the substantial damage, disability, and reduced quality of life that …

Novel therapeutics in psoriatic arthritis. What is in the pipeline?

O Elalouf, V Chandran - Current Rheumatology Reports, 2018 - Springer
Abstract Purpose of Review To highlight the recently approved therapeutic agents in
psoriatic arthritis (PsA), drugs in the pipeline, as well as to discuss efficacy with regard to …

Psoriatic arthritis

J Brockbank, DD Gladman - Expert Opinion on Investigational …, 2000 - Taylor & Francis
Psoriatic arthritis occurs in 5-42% of patients with psoriasis. It is an inflammatory arthritis
distinct from rheumatoid, being usually sero-negative, asymmetrical and often affecting the …

Psoriatic arthritis: latest treatments and their place in therapy

EJ Kang, A Kavanaugh - Therapeutic Advances in Chronic …, 2015 - journals.sagepub.com
Psoriatic arthritis (PsA) is a heterogeneous chronic inflammatory disease that may affect
peripheral and axial joints, entheses, skin and nails, and other organs. Treatment with …

Combination biologic treatment of refractory psoriasis and psoriatic arthritis

R Cuchacovich, I Garcia-Valladares… - The Journal of …, 2012 - jrheum.org
The pathophysiology of psoriasis and psoriatic arthritis (PsA) is dependent on a multistep
process that leads to chronic or recurrent inflammation1, 2, 3. Blockade of cytokines …