RNA viruses are unique in their evolutionary capacity, exhibiting high mutation rates and
frequent recombination. They rapidly adapt to environmental changes, such as shifts in …

RNA viruses provide unique insights into the patterns and processes of evolutionary change
in real time. The study of viral evolution is especially topical given the growing awareness …

The deterministic force of natural selection and stochastic influence of drift shape RNA virus
evolution. New deep-sequencing and microfluidics technologies allow us to quantify the …

RNA viruses face dynamic environments and are masters at adaptation. During their
short'lifespans', they must surmount multiple physical, anatomical and immunological …

RNA viruses are the main agents of emerging disease. To understand how RNA viruses are
able to jump species boundaries and spread in new hosts it is essential to determine the …

Geoghegan and Holmes describe the history of evolutionary ideas in the study of viruses,
showing that two different approaches to studying virus evolution—the comparative and the …

RNA viruses are notorious for rapidly generating genetically diverse populations during a
single replication cycle, and the implications of this mutant population, often referred to as …

RNA viruses are ubiquitous intracellular parasites that are responsible for many emerging
diseases, including AIDS and SARS. Here, we discuss the principal mechanisms of RNA …

RNA viruses are often thought of as possessing almost limitless adaptability as a result of
their extreme mutation rates. However, high mutation rates also put a cap on the size of the …

Gene overlapping is widely employed by RNA viruses to generate genetic novelty while
retaining a small genome size. However, gene overlapping also increases the deleterious …