Corticosteroid-modulated immune activation in the tuberculosis immune reconstitution inflammatory syndrome

G Meintjes, KH Skolimowska, KA Wilkinson… - American journal of …, 2012 - atsjournals.org
Rationale: HIV–tuberculosis-associated immune reconstitution inflammatory syndrome (TB-
IRIS) is an immunopathological reaction to mycobacterial antigens induced by antiretroviral …

The tuberculosis-associated immune reconstitution inflammatory syndrome: recent advances in clinical and pathogenesis research

NF Walker, C Stek, S Wasserman… - Current Opinion in …, 2018 - journals.lww.com
Specific biomarkers would aid in identifying high-risk patients for interventions and a
diagnostic test is needed. Clinicians should consider prednisone for TB-IRIS prevention in …

HIV-1 tuberculosis-associated immune reconstitution inflammatory syndrome

RPJ Lai, G Meintjes, RJ Wilkinson - Seminars in immunopathology, 2016 - Springer
Patients co-infected with HIV-1 and tuberculosis (TB) are at risk of developing TB-associated
immune reconstitution inflammatory syndrome (TB-IRIS) following commencement of …

Treatment for tuberculosis-associated immune reconstitution inflammatory syndrome in 34 HIV-infected patients

G Breton, A Bourgarit, S Pavy, D Bonnet… - … of tuberculosis and …, 2012 - ingentaconnect.com
BACKGROUND: Paradoxical tuberculosis immune reconstitution inflammatory syndrome
(TB-IRIS) frequently follows the initiation of antiretroviral therapy (ART) in patients with …

Hypercytokinaemia accompanies HIV–tuberculosis immune reconstitution inflammatory syndrome

R Tadokera, G Meintjes… - European …, 2011 - Eur Respiratory Soc
Increased access to combination antiretroviral therapy in areas co-endemic for tuberculosis
(TB) and HIV-1 infection is associated with an increased incidence of immune reconstitution …

Robust Reconstitution of Tuberculosis-Specific Polyfunctional CD4+ T-Cell Responses and Rising Systemic Interleukin 6 in Paradoxical Tuberculosis-Associated …

S Ravimohan, N Tamuhla, K Nfanyana… - Clinical Infectious …, 2016 - academic.oup.com
Background. The immunopathogenesis of paradoxical tuberculosis-associated immune
reconstitution inflammatory syndrome (TB-IRIS) remains unclear. We determined the …

Type 1 helper T cells and FoxP3-positive T cells in HIV–tuberculosis-associated immune reconstitution inflammatory syndrome

G Meintjes, KA Wilkinson, MX Rangaka… - American journal of …, 2008 - atsjournals.org
Rationale: Tuberculosis-associated immune reconstitution inflammatory syndrome (TB–
IRIS) induced by combination antiretroviral therapy (cART) has been attributed to …

[HTML][HTML] Cytotoxic mediators in paradoxical HIV–tuberculosis immune reconstitution inflammatory syndrome

KA Wilkinson, NF Walker, G Meintjes… - The Journal of …, 2015 - journals.aai.org
Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) frequently
complicates combined antiretroviral therapy and antituberculosis therapy in HIV-1 …

Lower pre-treatment T cell activation in early-and late-onset tuberculosis-associated immune reconstitution inflammatory syndrome

O Goovaerts, W Jennes, M Massinga-Loembé… - PloS one, 2015 - journals.plos.org
Background Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-
IRIS) is an inflammatory complication in HIV-TB co-infected patients receiving antiretroviral …

Immune reconstitution inflammatory syndrome of tuberculosis among HIV-infected patients receiving antituberculous and antiretroviral therapy

W Manosuthi, S Kiertiburanakul, T Phoorisri… - Journal of Infection, 2006 - Elsevier
OBJECTIVE: To determine the frequency, risk factors and mortality rate of immune
reconstitution inflammatory syndrome (IRIS) of tuberculosis (TB) in patients co-infected with …