Advancements in macrophage-targeted drug delivery for effective disease management

H Liu, H Lv, X Duan, Y Du, Y Tang… - International Journal of …, 2023 - Taylor & Francis
Macrophages play a crucial role in tissue homeostasis and the innate immune system. They
perform essential functions such as presenting antigens, regulating cytokines, and …

[HTML][HTML] Macrophage based drug delivery: Key challenges and strategies

Q Guo, ZM Qian - Bioactive Materials, 2024 - Elsevier
As a natural immune cell and antigen presenting cell, macrophages have been studied and
engineered to treat human diseases. Macrophages are well-suited for use as drug carriers …

Recent advances in macrophage-mediated drug delivery systems

T Liang, R Zhang, X Liu, Q Ding, S Wu… - International journal …, 2021 - Taylor & Francis
Macrophages have been extensively used in the development of drug delivery systems, as
they can prolong the circulation and release of drugs, extend their half-life, increase their …

Drug delivery to macrophages: A review of nano-therapeutics targeted approach for inflammatory disorders and cancer

M Mukhtar, H Ali, N Ahmed, R Munir… - Expert opinion on …, 2020 - Taylor & Francis
Introduction Macrophages are involved in the normal defense of the body; however, the
varying phenotypes of macrophages and imbalance in their ratio lead to the impairment of …

Active nano-targeting of macrophages

N Gaspar, G Zambito, CMWG Löwik… - Current …, 2019 - ingentaconnect.com
Macrophages play a role in almost every disease such as cancer, infections, injuries,
metabolic and inflammatory diseases and are becoming an attractive therapeutic target …

Targeted drug delivery to macrophages

NK Jain, V Mishra, NK Mehra - Expert opinion on drug delivery, 2013 - Taylor & Francis
Introduction: Targeted drug delivery to the macrophages appears to be an attractive
proposition to improve therapeutic efficacy of enclosed drug. Thus, macrophages can be …

Harnessing anti-inflammatory pathways and macrophage nano delivery to treat inflammatory and fibrotic disorders

A Zaid, A Ariel - Advanced Drug Delivery Reviews, 2024 - Elsevier
Targeting specific organs and cell types using nanotechnology and sophisticated delivery
methods has been at the forefront of applicative biomedical sciences lately. Macrophages …

Drug delivery to macrophages: challenges and opportunities

Y Pei, Y Yeo - Journal of Controlled Release, 2016 - Elsevier
Macrophages are prevalent in the body and have roles in almost every aspect of human
biology. They have often been considered a subject to avoid during drug delivery. However …

Drug delivery to macrophages: a review of targeting drugs and drug carriers to macrophages for inflammatory diseases

W He, N Kapate, CW Shields IV, S Mitragotri - Advanced drug delivery …, 2020 - Elsevier
Macrophages play a key role in defending against foreign pathogens, healing wounds, and
regulating tissue homeostasis. Driving this versatility is their phenotypic plasticity, which …

Current development of nano-drug delivery to target macrophages

D Cai, W Gao, Z Li, Y Zhang, L Xiao, Y Xiao - Biomedicines, 2022 - mdpi.com
Macrophages are the most important innate immune cells that participate in various
inflammation-related diseases. Therefore, macrophage-related pathological processes are …