Heart failure (HF) is a clinical syndrome caused by impairment of ventricular filling, ejection
of blood, or both and is categorized as HF with reduced ejection fraction (HFrEF) or HF with …

Aims MiR-181c-5p overexpression associates with heart failure (HF) and cardiac damage,
but the underlying pathophysiology remains unclear. This study investigated the effect of …

Objective MicroRNAs (miRNAs), a group of small non-coding RNAs that fine tune translation
of multiple target mRNAs, have been implicated in the development and progression of …

Cardiac remodeling can cause ventricular dysfunction and progress to heart failure, a
cardiovascular disease that claims many lives globally. Ivabradine, a funny channel (I f) …

Pathological cardiac hypertrophy often precedes heart failure due to various stimuli, yet
effective clinical interventions remain limited. Recently, microRNAs (miRNAs) have been …

Advanced diabetes mellitus (DM) may have both insulin resistance and deficiency (double
DM) that accelerates diabetic cardiomyopathy (DMCM), a cardiac muscle disorder. Reduced …

Betalain is a natural plant pigment known to elicit various biological activities. However,
studies on the protective effect of betalain against heart failure have not reported yet. The …

Background: Numerous studies have highlighted the crucial role of microRNA-145 (miR-
145) in coronary atherosclerosis and myocardial ischemia reperfusion injury. However …

Cardiac fibrosis is a major pathological manifestation of diabetic cardiomyopathy, which is a
leading cause of mortality in patients with diabetes. MicroRNA (miR)-155 is upregulated in …

The aim of the present study was to determine the effect of microRNA (miR)-132 on cardiac
fibrosis in myocardial infarction (MI)-induced heart failure and angiotensin (Ang) II-treated …