Isolated mangiferin and naringenin exert antidiabetic effect via PPARγ/GLUT4 dual agonistic action with strong metabolic regulation
In this study, we isolated two compounds from the leaves of Salacia oblonga (SA1,
mangiferin and SA2, naringenin), and their structures were confirmed by infrared …
mangiferin and SA2, naringenin), and their structures were confirmed by infrared …
Insulin sensitization via partial agonism of PPARγ and glucose uptake through translocation and activation of GLUT4 in PI3K/p-Akt signaling pathway by embelin in …
BACKGROUND: The present study was aimed at isolating an antidiabetic molecule from a
herbal source and assessing its mechanism of action. METHODS: Embelin, isolated from …
herbal source and assessing its mechanism of action. METHODS: Embelin, isolated from …
Mangiferin from Salacia chinensis Prevents Oxidative Stress and Protects Pancreatic β-Cells in Streptozotocin-Induced Diabetic Rats
PS Sellamuthu, P Arulselvan, BP Muniappan… - Journal of medicinal …, 2013 - liebertpub.com
Oxidative stress in diabetic tissues is a consequence of free radical accumulation with
concurrently impaired natural antioxidants status and results in oxidative tissue damage …
concurrently impaired natural antioxidants status and results in oxidative tissue damage …
Anti-diabetic activity and potential mechanism of total flavonoids of Selaginella tamariscina (Beauv.) Spring in rats induced by high fat diet and low dose STZ
X Zheng, L Zhang, W Wang, Y Wu, Q Zhang… - Journal of …, 2011 - Elsevier
AIM OF THE STUDY: To evaluate the anti-diabetic effects of the total flavonoids of
Selaginella tamariscina (Beauv.) Spring (TFST), and to explore the pertinent mechanism …
Selaginella tamariscina (Beauv.) Spring (TFST), and to explore the pertinent mechanism …
Peroxisome proliferator-activated receptor activating hypoglycemic effect of Gardenia jasminoides Ellis aqueous extract and improvement of insulin sensitivity in …
YI Chen, YW Cheng, CY Tzeng, YC Lee… - … and Alternative Medicine, 2014 - Springer
Background The active components of Gardenia (Gardenia jasminoides Ellis, GJ) exhibit a
hypoglycemic effect by improving insulin secretion and lowering plasma lipids. In the …
hypoglycemic effect by improving insulin secretion and lowering plasma lipids. In the …
[HTML][HTML] Mangosteen xanthone γ-mangostin exerts lowering blood glucose effect with potentiating insulin sensitivity through the mediation of AMPK/PPARγ
Diabetes mellitus (DM) is concomitant with significant morbidity and mortality and its
prevalence is accumulative in worldwide. The conventional antidiabetic agents are known to …
prevalence is accumulative in worldwide. The conventional antidiabetic agents are known to …
Ginsenoside Rb1 as an anti-diabetic agent and its underlying mechanism analysis
P Zhou, W Xie, S He, Y Sun, X Meng, G Sun, X Sun - Cells, 2019 - mdpi.com
Panax ginseng and Panax notoginseng, two well-known medical plants with economic
value, have a long history of use for managing various diseases in Asian countries …
value, have a long history of use for managing various diseases in Asian countries …
Luteolin‐Rich Extract of Thespesia garckeana F. Hoffm. (Snot Apple) Contains Potential Drug‐Like Candidates and Modulates Glycemic and Oxidoinflammatory …
The present study evaluated the polyphenolic contents and hypoglycemic, antioxidant, and
anti‐inflammatory effects of the diethyl ether fraction of Thespesia garckeana using various …
anti‐inflammatory effects of the diethyl ether fraction of Thespesia garckeana using various …
Antidiabetic effect of a flavonoid-rich extract from Sophora alopecuroides L. in HFD-and STZ-induced diabetic mice through PKC/GLUT4 pathway and regulating …
Y Lv, P Zhao, K Pang, Y Ma, H Huang, T Zhou… - Journal of …, 2021 - Elsevier
Headings ethnopharmacological relevance Sophora alopecuroides L. is a traditional
ethnopharmacological plant, which is widely used in traditional Chinese medicine and …
ethnopharmacological plant, which is widely used in traditional Chinese medicine and …
Triterpenoid Saponins from Stauntonia chinensis Ameliorate Insulin Resistance via the AMP-Activated Protein Kinase and IR/IRS-1/PI3K/Akt Pathways in Insulin …
X Hu, S Wang, J Xu, DB Wang, Y Chen… - International journal of …, 2014 - mdpi.com
Inflammation and oxidative stress play crucial roles in the etiology of type 2 diabetes
mellitus. In this study, we examined the anti-diabetic effects of triterpenoid saponins …
mellitus. In this study, we examined the anti-diabetic effects of triterpenoid saponins …