[HTML][HTML] From multi-omics approaches to precision medicine in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a devastating and fatal neurodegenerative disorder,
caused by the degeneration of upper and lower motor neurons for which there is no truly …
caused by the degeneration of upper and lower motor neurons for which there is no truly …
The 'omics' of amyotrophic lateral sclerosis
D Caballero-Hernandez, MG Toscano… - Trends in molecular …, 2016 - cell.com
Amyotrophic lateral sclerosis (ALS) is a rare neurodegenerative disease that primarily
affects motor neurons and is accompanied by sustained unregulated immune responses …
affects motor neurons and is accompanied by sustained unregulated immune responses …
[HTML][HTML] Amyotrophic lateral sclerosis: a neurodegenerative disorder poised for successful therapeutic translation
Amyotrophic lateral sclerosis (ALS) is a devastating disease caused by degeneration of
motor neurons. As with all major neurodegenerative disorders, development of disease …
motor neurons. As with all major neurodegenerative disorders, development of disease …
[HTML][HTML] A systematic review of suggested molecular strata, biomarkers and their tissue sources in ALS
UG Vijayakumar, V Milla, MY Cynthia Stafford… - Frontiers in …, 2019 - frontiersin.org
Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease, is an incurable
neurodegenerative condition, characterized by the loss of upper and lower motor neurons. It …
neurodegenerative condition, characterized by the loss of upper and lower motor neurons. It …
Amyotrophic lateral sclerosis: a focus on disease progression
AC Calvo, R Manzano, DMF Mendonça… - BioMed research …, 2014 - Wiley Online Library
Since amyotrophic lateral sclerosis (ALS) was discovered and described in 1869 as a
neurodegenerative disease in which motor neuron death is induced, a wide range of …
neurodegenerative disease in which motor neuron death is induced, a wide range of …
[HTML][HTML] Integrative multi-omic analysis identifies new drivers and pathways in molecularly distinct subtypes of ALS
Amyotrophic lateral sclerosis (ALS) is an incurable and fatal neurodegenerative disease.
Increasing the chances of success for future clinical strategies requires more in-depth …
Increasing the chances of success for future clinical strategies requires more in-depth …
[HTML][HTML] Toward precision medicine in amyotrophic lateral sclerosis
ZY Zou, CY Liu, CH Che, HP Huang - Annals of translational …, 2016 - ncbi.nlm.nih.gov
Precision medicine is an innovative approach that uses emerging biomedical technologies
to deliver optimally targeted and timed interventions, customized to the molecular drivers of …
to deliver optimally targeted and timed interventions, customized to the molecular drivers of …
Biomarkers in amyotrophic lateral sclerosis: opportunities and limitations
Insights into the mechanisms of amyotrophic lateral sclerosis (ALS) have relied
predominantly on the study of postmortem tissue. Modern technology has improved the …
predominantly on the study of postmortem tissue. Modern technology has improved the …
Therapeutic targeting of ALS pathways: Refocusing an incomplete picture
NJ Maragakis, M de Carvalho… - Annals of Clinical and …, 2023 - Wiley Online Library
Numerous potential amyotrophic lateral sclerosis (ALS)‐relevant pathways have been
hypothesized and studied preclinically, with subsequent translation to clinical trial. However …
hypothesized and studied preclinically, with subsequent translation to clinical trial. However …
Biomarkers for amyotrophic lateral sclerosis
S Witzel, K Mayer, P Oeckl - Current Opinion in Neurology, 2022 - journals.lww.com
Biomarkers for amyotrophic lateral sclerosis : Current Opinion in Neurology Biomarkers for
amyotrophic lateral sclerosis : Current Opinion in Neurology Log in or Register Subscribe to …
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