Z-DNA stabilization is dominated by the Hofmeister effect
The manner in which Z-DNA is stabilized at high salt concentrations remains unclear. Here,
we systematically examine the Z-DNA-stabilizing capabilities of different salts. The strong …
we systematically examine the Z-DNA-stabilizing capabilities of different salts. The strong …
[PDF][PDF] Contribution of counterion entropy to the salt-induced transition between B-DNA and Z-DNA
Formation of Z-DNA, a left-handed double helix, from B-DNA, the canonical right-handed
double helix, occurs during important biological processes such as gene expression and …
double helix, occurs during important biological processes such as gene expression and …
The electrostatic contribution to the B to Z transition of DNA
In this paper, the finite difference nonlinear Poisson− Boltzmann (NLPB) equation is used to
calculate the electrostatic contribution to the B to Z transition of DNA using detailed …
calculate the electrostatic contribution to the B to Z transition of DNA using detailed …
DNA bending force facilitates Z-DNA formation under physiological salt conditions
Z-DNA, a noncanonical helical structure of double-stranded DNA (dsDNA), plays pivotal
roles in various biological processes, including transcription regulation. Mechanical stresses …
roles in various biological processes, including transcription regulation. Mechanical stresses …
Cooperativity effects between non-covalent interactions: Are they important for Z-DNA stability?
We have analyzed the non-covalent interactions observed in the Z-DNA structure by
examining structures retrieved from the nucleic database (NDB) and by using high level ab …
examining structures retrieved from the nucleic database (NDB) and by using high level ab …
Advancements in Z-DNA: development of inducers and stabilizers for B to Z transition
Z-DNA, an active element in genome, has drawn intense interest in chemical and biological
field. Its dynamic and transient state makes it challenging to target and regulate. Thus …
field. Its dynamic and transient state makes it challenging to target and regulate. Thus …
Intrinsic Z-DNA is stabilized by the conformational selection mechanism of Z-DNA-binding proteins
Z-DNA, a left-handed isoform of Watson and Crick's B-DNA, is rarely formed without the help
of high salt concentrations or negative supercoiling. However, Z-DNA-binding proteins can …
of high salt concentrations or negative supercoiling. However, Z-DNA-binding proteins can …
Investigation of BZ transitions with DNA oligonucleotides containing 8-methylguanine
Among various Z-form DNA inducers, such as transition metal complexes, polyamines and
high ionic concentrations, 8-methylguanine have received attention as efficient chemical …
high ionic concentrations, 8-methylguanine have received attention as efficient chemical …
Sequence-specific B-DNA flexibility modulates Z-DNA formation
JR Bothe, K Lowenhaupt… - Journal of the American …, 2011 - ACS Publications
Conversion of right-handed B-DNA into left-handed Z-DNA is one of the largest structural
transitions in biology that plays fundamental roles in gene expression and regulation. Z-DNA …
transitions in biology that plays fundamental roles in gene expression and regulation. Z-DNA …
The role of the molecular shape on the conformational transition from B-to Z-DNA
JLF Abascal, JC Gil Montoro - The Journal of chemical physics, 1999 - pubs.aip.org
Apart from its possible biological relevance, 1 the conformational equilibrium between the B
and Z forms of DNA2 has been the topic of several theoretical studies due to the dramatic …
and Z forms of DNA2 has been the topic of several theoretical studies due to the dramatic …