We performed a two-step polymerase chain reaction (PCR) to detect bcr-abl-specific mRNA
in 440 peripheral blood and/or bone marrow samples of 30 chronic myeloid leukemia (CML) …

We report here the results of polymerase chain reaction (PCR) for bcr-abl transcript and
clinical details derived from 64 chronic myelogenous leukemia (CML) patients after …

BACKGROUND. Chronic myeloid leukemia (CML) is a disease characterized by the
presence of a unique molecular marker, ie the fusion gene bcr-abl and its mRNA and protein …

The bcr-abl chimeric messenger RNA is frequently detected in chronic myeloid leukemia
(CML) patients after bone marrow transplantation. It was previously reported that the relapse …

Previous studies have shown that tumor-specific bcr-abl mRNA can often be detected by
polymerase chain reaction.(PCR) for months to years after allogeneic bone marrow …

Relapse of chronic myelogenous leukemia after bone marrow transplantation can be
detected by using clinical, cytogenetic, or molecular tools. A modification of the polymerase …

A modified two-step polymerase chain reaction (PCR) was used for the amplification of
BCR/ABL mRNA in 16 patients with Philadelphia chromosomepositive (Ph+) chronic …

Quantitative competitive RT-PCR techniques have been developed to detect BCR-ABL
fusion transcripts in CML but they are hardly reproducible. In this work, we have developed …

In chronic myelogenous leukemia (CML), amplification of a segment of bcr-abl messenger
RNA (mRNA) by polymerase chain reaction (PCR) can be used to detect minimal residual …

The polymerase chain reaction (PCR) allows the detection of minimal amounts of nucleic
sequences and has been successfully used to test for the chronic myeloid leukemia-specific …