Computed tomography has facilitated recognition that chronic obstructive pulmonary
disease is not a single disease but encompasses several overlapping entities, including …

Tobacco smoking is a risk factor for both pulmonary disease and atherosclerosis and a
number of studies have provided both experimental and epidemiological evidence about the …

Chronic obstructive pulmonary disease (COPD) is a complex genetic disorder in which
environmental factors, such as tobacco smoke, interact with genetic susceptibility to cause …

Although the human and societal burden and cost of COPD is staggering, there are few
clinical tools that provide earlier diagnoses or a means to regionally monitor disease in a …

Background: Exacerbation episodes are a significant cause of morbidity and healthcare
utilization in individuals with bronchiectasis and COPD and are considered key endpoints to …

Rationale and Objectives Many patients with chronic obstructive pulmonary disease (COPD)
have marked discordance between forced expiratory volume in 1 second (FEV 1) and …

Chronic obstructive pulmonary disease is a syndrome that encompasses a variety of
pathologies and underlying mechanisms. Progress in understanding mechanisms, testing …

A new method of quantitative computed tomography (CT) measurements of pulmonary
vessels are applicable to morphological studies and may be helpful in defining the …

Whether COPD is generally known as a small airway disease, recent investigations suggest
that vascular remodeling could play a key role in disease progression. This paper develops …

While the recent development of quantitative imaging methods have led to their increased
use in the diagnosis and management of many chronic diseases, medical imaging still plays …