Autocrine motility factor secreted by tumor cells upregulates vascular endothelial growth factor receptor (Flt‐1) expression in endothelial cells

T Funasaka, A Haga, A Raz… - International journal of …, 2002 - Wiley Online Library
The autocrine motility factor (AMF) is known as a cytokine regulating tumor cells motility via
AMF receptor (AMFR) and promotes their metastasis. Recently, AMFRs have been found on …

Novel roles of the autocrine motility factor/phosphoglucose isomerase in tumor malignancy

T Yanagawa, T Funasaka, S Tsutsumi… - Endocrine-Related …, 2004 - erc.bioscientifica.com
Autocrine motility factor (AMF) stimulates cell motility in an autocrine manner and is related
to tumor malignancy. AMF is a multifunctional molecule, also known as phosphoglucose …

Tumor cell autocrine motility factor is the neuroleukin/phosphohexose isomerase polypeptide

H Watanabe, K Takehana, M Date, T Shinozaki, A Raz - Cancer research, 1996 - AACR
To date, the structure of the autocrine motility factor (AMF), a tumorsecreted cytokine which
stimulates cell migration in vitro and metastasis in vivo, is unknown. Here, AMF secreted by …

Silencing of autocrine motility factor induces mesenchymal-to-epithelial transition and suppression of osteosarcoma pulmonary metastasis

Y Niinaka, K Harada, M Fujimuro, M Oda, A Haga… - Cancer research, 2010 - AACR
Phosphoglucose isomerase (PGI) is a multifunctional enzyme that functions in glucose
metabolism as a glycolytic enzyme catalyzing an interconversion between glucose and …

[HTML][HTML] Overexpression of autocrine motility factor in metastatic tumor cells: possible association with augmented expression of KIF3A and GDI-β

T Yanagawa, H Watanabe, T Takeuchi, S Fujimoto… - Laboratory …, 2004 - Elsevier
Autocrine motility factor (AMF), which is identical to phosphohexose isomerase
(PHI)/glucose-6-phosphate isomerase (GPI), a ubiquitous enzyme essential for glycolysis …

The autocrine motility factor (AMF) and AMF-receptor combination needs sugar chain recognition ability and interaction using the C-terminal region of AMF

A Haga, N Tanaka, T Funasaka, K Hashimoto… - Journal of molecular …, 2006 - Elsevier
The autocrine motility factor (AMF) promotes cellular locomotion or invasion, and regulates
tumor angiogenesis or ascites accumulation. These signals are triggered by binding …

Purification of human tumor cell autocrine motility factor and molecular cloning of its receptor

H Watanabe, P Carmi, V Hogan, T Raz, S Silletti… - Journal of Biological …, 1991 - Elsevier
Tumor autocrine motility factor (AMF) has been detected in and purified from serum-free
conditioned medium of human HT-1080 fibrosarcoma cells. Under nonreducing conditions …

Autocrine motility factor-receptor gene expression in lung cancer

I Takanami, K Takeuchi - The Japanese Journal of Thoracic and …, 2003 - Springer
Objective: Autocrine motility factor (AMF) stimulates cell motility via binding its receptor (AMF-
R) and AMF-R is engaged in tumor cell motility and the AMF-R gene expression level may …

Expression and function of autocrine motility factor receptor in human choriocarcinoma

FD Yelian, A Liu, JC Todt, J Lei, F Qureshi… - Gynecologic …, 1996 - Elsevier
Objective: Our purpose was to determine whether human choriocarcinoma cells express
autocrine motility factor receptor (AMF-R) and to study its function in this tumor system. Study …

Autocrine motility factor signaling induces tumor apoptotic resistance by regulations Apaf‐1 and Caspase‐9 apoptosome expression

A Haga, T Funasaka, Y Niinaka, A Raz… - … journal of cancer, 2003 - Wiley Online Library
Autocrine motility factor (AMF) is a cytokine that regulates locomotion and metastasis of
tumor cells. It is well known that expression levels of AMF secretion and its receptor (AMF R) …