Expression of autocrine motility factor receptor in cutaneous malignant melanoma

Y Nagai, O Ishikawa, Y Miyachi, H Watanabe - Dermatology, 1996 - karger.com
Background: The autocrine motility factor receptor (AMFR), a specific receptor for AMF, is
considered to be related to the metastatic potential of tumor cells. Objective: We investigated …

Tumor autocrine motility factor responses are mediated through cell contact and focal adhesion rearrangement in the absence of new tyrosine phosphorylation in …

S Silletti, S Paku, A Raz - The American journal of pathology, 1996 - ncbi.nlm.nih.gov
Autocrine motility factor (AMF) is a tumor-secreted cytokine that acts as a motogen as well as
a mitogen via a receptor-mediated signaling pathway (s). Expression of the AMF receptor …

Prognostic significance of autocrine motility factor receptor expression by colorectal cancer and lymph node metastases

Y Halwani, LD Kojic, SK Chan, TP Phang… - The American Journal of …, 2015 - Elsevier
Background Autocrine motility factor receptor (AMFR) has been linked to metastasis and
tumorigenicity. The aim of this study was to evaluate expression and prognostic significance …

Expression of autocrine motility factor receptor correlates with disease progression in human gastric cancer

Y Hirono, S Fushida, Y Yonemura, H Yamamoto… - British journal of …, 1996 - nature.com
Up-regulation of autocrine motility factor receptor (AMF-R) expression has been shown to be
associated with invasion and metastasis of experimental tumour systems and human …

Phosphoglucose isomerase/autocrine motility factor promotes melanoma cell migration through ERK activation dependent on autocrine production of interleukin-8

K Araki, T Shimura, T Yajima, S Tsutsumi… - Journal of Biological …, 2009 - ASBMB
It is well known that phosphoglucose isomerase/autocrine motility factor (AMF) promotes cell
migration in an autocrine manner in various tumor cells. However, it remains unclear …

Higher autocrine motility factor/glucose-6-phosphate isomerase expression is associated with tumorigenesis and poorer prognosis in gastric cancer

YT Ma, XF Xing, B Dong, XJ Cheng, T Guo… - Cancer management …, 2018 - Taylor & Francis
Background Glucose-6-phosphate isomerase (GPI) is a glycolytic-related enzyme that inter-
converts glucose-6-phosphate and fructose-6-phosphate in the cytoplasm. This protein is …

[HTML][HTML] AMF/PGI-mediated tumorigenesis through MAPK-ERK signaling in endometrial carcinoma

Y Li, Y Jia, Q Che, Q Zhou, K Wang, XP Wan - Oncotarget, 2015 - ncbi.nlm.nih.gov
Autocrine motility factor (AMF), which is also known as phosphoglucose isomerase (PGI),
enhances tumor cell growth and motility. In this study, we found that AMF and its receptor …

Tumor autocrine motility factor is an angiogenic factor that stimulates endothelial cell motility

T Funasaka, A Haga, A Raz, H Nagase - Biochemical and biophysical …, 2001 - Elsevier
Autocrine motility factor (AMF) is a type of tumor-secreted cytokine which primarily stimulates
tumor cell motility via receptor-mediated signaling pathways, and is thought to be connected …

Comparison of autocrine mechanisms promoting motility in two metastatic cell lines: Human melanoma and ras‐transfected NIH3T3 cells

M Seiki, H Sato, LA Liotta… - International journal of …, 1991 - Wiley Online Library
Tumor‐cell migration plays an essential role in invasion into surrounding tissues and the
formation of metastatic colonies in distant organs. Metastatic human A2058 melanoma and …

Regulation of cell motility via high and low affinity autocrine motility factor (AMF) receptor in human oral squamous carcinoma cells

Y Niinaka, A Haga, A Negishi, H Yoshimasu, A Raz… - Oral oncology, 2002 - Elsevier
A tumour-secreted cytokine autocrine motility factor (AMF) induces in vivo invasion and
metastasis, and in vitro tumour cell motility by a signal transduction through interaction with …