Decreased default mode network connectivity correlates with age-associated structural and cognitive changes

D Vidal-Piñeiro, C Valls-Pedret… - Frontiers in aging …, 2014 - frontiersin.org
Ageing entails cognitive and motor decline as well as brain changes such as loss of gray
(GM) and white matter (WM) integrity, neurovascular and functional connectivity alterations …

The longitudinal trajectory of default mode network connectivity in healthy older adults varies as a function of age and is associated with changes in episodic memory …

AM Staffaroni, JA Brown, KB Casaletto… - Journal of …, 2018 - Soc Neuroscience
The default mode network (DMN) supports memory functioning and may be sensitive to
preclinical Alzheimer's pathology. Little is known, however, about the longitudinal trajectory …

[HTML][HTML] Longitudinal functional connectivity patterns of the default mode network in healthy older adults

B Malagurski, PF Deschwanden, L Jäncke, S Mérillat - NeuroImage, 2022 - Elsevier
Cross-sectional studies have consistently identified age-associated alterations in default
mode network (DMN) functional connectivity (FC). Yet, research on longitudinal trajectories …

A longitudinal study of changes in resting-state functional magnetic resonance imaging functional connectivity networks during healthy aging

M Oschmann, JR Gawryluk… - Brain …, 2020 - liebertpub.com
Background: Vast increases in life expectancy over the last century have led to shifts in
population demographics and the emergence of a largely aged population, globally. This …

Age differences in the intrinsic functional connectivity of default network subsystems

KL Campbell, O Grigg, C Saverino… - Frontiers in aging …, 2013 - frontiersin.org
Recent work suggests that the default mode network (DMN) includes two core regions, the
ventromedial prefrontal cortex and posterior cingulate cortex (PCC), and several unique …

Aging and functional brain networks

D Tomasi, ND Volkow - Molecular psychiatry, 2012 - nature.com
Aging is associated with changes in human brain anatomy and function and cognitive
decline. Recent studies suggest the aging decline of major functional connectivity hubs in …

Longitudinal assessment of default-mode brain function in aging

J Persson, S Pudas, LG Nilsson, L Nyberg - Neurobiology of aging, 2014 - Elsevier
Age-related changes in the default-mode network (DMN) have been identified in prior cross-
sectional functional magnetic resonance imaging studies. Here, we investigated longitudinal …

Longitudinal reproducibility of default-mode network connectivity in healthy elderly participants: a multicentric resting-state fMRI study

J Jovicich, L Minati, M Marizzoni, R Marchitelli… - Neuroimage, 2016 - Elsevier
To date, limited data are available regarding the inter-site consistency of test–retest
reproducibility of functional connectivity measurements, in particular with regard to integrity …

Age-related alterations in default mode network: impact on working memory performance

F Sambataro, VP Murty, JH Callicott, HY Tan, S Das… - Neurobiology of …, 2010 - Elsevier
The default mode network (DMN) is a set of functionally connected brain regions which
shows deactivation (task-induced deactivation, TID) during a cognitive task. Evidence shows …

The role of resting-state network functional connectivity in cognitive aging

HK Hausman, A O'Shea, JN Kraft… - Frontiers in Aging …, 2020 - frontiersin.org
Aging is associated with disruptions in the resting-state functional architecture of the brain.
Previous studies have primarily focused on age-related declines in the default mode …