Bet v 1 is a 17-kDa protein abundantly present in the pollen of the White birch tree and is the
primary cause of birch pollen allergy in humans. Its three-dimensional structure is …

The major birch pollen allergen Bet v 1 is the main elicitor of airborne type I allergies and
belongs to the PR-10 family (pathogenesis-related proteins 10). Bet v 1 is the most …

Bet v 1, the major allergen of birch pollen, displays a considerable degree of heterogeneity.
Several charge variants have been detected by two-dimensional IgE immunoblots and …

The ability of pathogenesis-related proteins of family 10 to bind a broad spectrum of ligands
is considered to play a key role for their physiological and pathological functions. In …

The term allergy was coined in 1906 by the Austrian scientist and pediatrician Clemens
Freiherr von Pirquet. In 1976, Dietrich Kraft became the head of the Allergy and Immunology …

The 159 residue Bet v 1 is the major allergen from birch tree pollen. Its natural function is
unknown although it is capable of binding several types of physiologically relevant ligands …

Pollen from trees of the order Fagales (eg birch, alder, hazel, oak, and hornbeam) are a
major cause of Type I allergies observed in early spring. Previously, we reported the cloning …

BACKGROUND: Engineered hypoallergens are currently being investigated for specific
immunotherapy of allergic diseases in preclinical and clinical studies. Naturally occurring …

Abstract Background Pollen of the European white birch (Betula pendula, syn. B. verrucosa)
is an important cause of hay fever. The main allergen is Bet v 1, member of the pathogenesis …

Bet v 1, the major birch pollen allergen, is a member of a multigene family; a number of
isoforms and homologous proteins from closely related species (alder, hazel and hornbeam) …