Spinal serotonergic receptors mediate facilitation of a nociceptive reflex by subcutaneous formalin injection into the hindpaw in rats

AA Calejesan, HC Michael, M Zhuo - Brain research, 1998 - Elsevier
It is documented that spinal nociceptive transmission receives descending facilitatory and
inhibitory modulation from supraspinal structures. The rostral ventral medulla (RVM) …

Stimulation-produced descending inhibition from the periaqueductal gray and nucleus raphe magnus in the rat: mediation by spinal monoamines but not opioids

LD Aimone, SL Jones, GF Gebhart - Pain, 1987 - journals.lww.com
Focal electrical stimulation in the midbrain periaqueductal gray (PAG) or medullary nucleus
raphe magnus (NRM) inhibits spinal nociceptive transmission and nociceptive reflexes. The …

Spinal serotonergic and kappa opioid receptors mediate facilitation of the tail flick reflex produced by vagal afferent stimulation

K Ren, A Randich, GF Gebhart - Pain, 1991 - Elsevier
Facilitation of the nociceptive tail flick (TF) reflex produced by low intensity (2.0 msec, 20 Hz)
electrical stimulation of cervical vagal afferents (VAS) was studied in rats lightly anesthetized …

Characterization of inhibition of a spinal nociceptive reflex by stimulation medially and laterally in the midbrain and medulla in the pentobarbital-anesthetized rat

J Sandkühler, GF Gebhart - Brain research, 1984 - Elsevier
Inhibition of the spinal nociceptive tail flick (TF) reflex by electrical stimulation throughout the
midbrain and medulla was examined and characterized in pentobarbital-anesthetized rats …

Characterization of inhibition of the spinal nociceptive tail-flick reflex in the rat from the medullary lateral reticular nucleus

GF Gebhart, MH Ossipov - Journal of neuroscience, 1986 - Soc Neuroscience
Inhibition of the spinal nociceptive tail-flick (TF) reflex by focal electrical stimulation in the
caudal medulla was examined and characterized in lightly pentobarbital-anesthetized rats …

Stimulation-produced spinal inhibition from the midbrain in the rat is mediated by an excitatory amino acid neurotransmitter in the medial medulla

LD Aimone, GF Gebhart - Journal of Neuroscience, 1986 - Soc Neuroscience
It has been previously established that a bulbar relay plays an important role in descending
inhibition of spinal dorsal horn nociceptive neurons and nociceptive reflexes produced by …

Dual effect of serotonin on formalin-induced nociception in the rat spinal cord

T Oyama, M Ueda, Y Kuraishi, A Akaike, M Satoh - Neuroscience research, 1996 - Elsevier
To examine the role of the descending serotonergic system in the regulation of spinal
nociceptive processing, the effects of serotonin (5-HT) and selective ligands for 5-HT …

Characterization of coeruleospinal inhibition of the nociceptive tail-flick reflex in the rat: mediation by spinal α2-adrenoceptors

SL Jones, GF Gebhart - Brain research, 1986 - Elsevier
Several lines of evidence implicate bulbospinal noradrenergic pathways in antinociception
and descending inhibition. In the present study, descending inhibition of the nociceptive tail …

Biphasic modulation of spinal nociceptive transmission from the medullary raphe nuclei in the rat

M Zhuo, GF Gebhart - Journal of neurophysiology, 1997 - journals.physiology.org
Zhuo, M. and GF Gebhart. Biphasic modulation of spinal nociceptive transmission from the
medullary raphe nuclei in the rat. J. Neurophysiol. 78: 746–758, 1997. The modulatory …

Spinal serotonin receptors mediate descending facilitation of a nociceptive reflex from the nuclei reticularis gigantocellularis and gigantocellularis pars alpha in the rat

M Zhuo, GF Gebhart - Brain research, 1991 - Elsevier
Electrical stimulation in the nucleus reticularis gigantocellularis (NGC) and gigantocellularis
pars alpha (NGCα) produces facilitation and/or inhibition of spinal nociceptive transmission …