Pregnancy is a pro-inflammatory/hypercoagulable state. Impairment of trophoblastic
invasion and placental microthrombi are involved mechanisms in the pathogenesis of …

BACKGROUND: Circulating microparticles are markers of cell activation associated with
various prothrombotic states. As hypoxia due to uteroplacental thrombosis is considered to …

Microparticles are submicronic phospholipid vesicles, 041–1 μm in size, derived from
different cells during activation or apoptosis. The majority of MPs express …

Microparticles (MPs) are shed from cell membranes of a variety of cells, promote thrombus
formation, mediate pro-inflammatory effects and may cause endothelial dysfunction. Normal …

The multiple functions attributed to microparticles (MPs) include blood coagulation,
inflammation, tumorigenesis, angiogenesis, immunomodulatory functions and intercellular …

The antiphospholipid syndrome (APS) refers to persistent antiphospholipid antibodies (aPL)
associated with thrombotic and/or obstetrical complications. The endothelial cell is a target …

Pregnancy is an acquired hypercoagulable state, with gestational vascular complications
(GVC) including preeclampsia, intrauterine growth restriction (IUGR), pregnancy loss and …

Background: Microparticles (MP) are pro-coagulant vesicles derived from various cells.
Evidence is accumulating that MP are of pathophysiological relevance in autoimmune …

Microparticles (MPs) have been associated with inflammatory and thrombotic disease. High
levels of MPs have been identified in patients with systemic lupus erythematosus (SLE) and …

Background 15% of reproducing couples suffer from pregnancy loss (PL) and recurs in 2-
3%. One of the most frequently hypothesized causes of unexplained PL refers to a defective …