[HTML][HTML] Systems biology–A guide for understanding and developing improved strains of lactic acid bacteria

J Liu, SHJ Chan, J Chen, C Solem… - Frontiers in …, 2019 - frontiersin.org
Lactic Acid Bacteria (LAB) are extensively employed in the production of various fermented
foods, due to their safe status, ability to affect texture and flavor and finally due to the …

Recent trends in metabolic engineering of microbial chemical factories

Y Liu, J Nielsen - Current opinion in biotechnology, 2019 - Elsevier
Highlights•Microbial cell factories can be tailored for producing certain 'drop-in'chemicals.•
Metabolic engineering has greatly enhanced the development of microbial cell …

Modular co-culture engineering, a new approach for metabolic engineering

H Zhang, X Wang - Metabolic engineering, 2016 - Elsevier
With the development of metabolic engineering, employment of a selected microbial host for
accommodation of a designed biosynthetic pathway to produce a target compound has …

Tools and strategies of systems metabolic engineering for the development of microbial cell factories for chemical production

YS Ko, JW Kim, JA Lee, T Han, GB Kim… - Chemical Society …, 2020 - pubs.rsc.org
Sustainable production of chemicals from renewable non-food biomass has become a
promising alternative to overcome environmental issues caused by our heavy dependence …

Construction and optimization of synthetic pathways in metabolic engineering

D Na, TY Kim, SY Lee - Current opinion in microbiology, 2010 - Elsevier
Metabolic engineering has enabled us to develop strains suitable for their use as microbial
factories of chemicals and materials from renewable sources. It has recently become more …

Microbial production of value-added nutraceuticals

J Wang, S Guleria, MAG Koffas, Y Yan - Current opinion in biotechnology, 2016 - Elsevier
Highlights•Nutraceuticals are health-promoting compounds of diverse structures and
origins.•Metabolic engineering enables microbes for value-added nutraceutical …

Metabolic engineering of industrial platform microorganisms for biorefinery applications–optimization of substrate spectrum and process robustness by rational and …

N Buschke, R Schäfer, J Becker, C Wittmann - Bioresource technology, 2013 - Elsevier
Bio-based production promises a sustainable route to myriads of chemicals, materials and
fuels. With regard to eco-efficiency, its future success strongly depends on a next level of bio …

Production of plant metabolites with applications in the food industry using engineered microorganisms

N Kallscheuer, T Classen, T Drepper… - Current opinion in …, 2019 - Elsevier
Highlights•Plant metabolites have numerous applications in the food industry.•Most plant
metabolites with food applications are (poly) phenols and terpenoids.•Microorganisms can …

Microbial chassis development for natural product biosynthesis

X Xu, Y Liu, G Du, R Ledesma-Amaro, L Liu - Trends in biotechnology, 2020 - cell.com
Engineering microbial cells to efficiently synthesize high-value-added natural products has
received increasing attention in recent years. In this review, we describe the pipeline to build …

Exploiting unconventional prokaryotic hosts for industrial biotechnology

B Blombach, A Grünberger, F Centler, N Wierckx… - Trends in …, 2022 - cell.com
Developing cost-efficient biotechnological processes is a major challenge in replacing fossil-
based industrial production processes. The remarkable progress in genetic engineering …