KRT18 is correlated with the malignant status and acts as an oncogene in colorectal cancer

J Zhang, S Hu, Y Li - Bioscience reports, 2019 - portlandpress.com
Abstract Keratin 18 (KRT18) has been suggested to be overexpressed in most types of
human tumor, but the expression pattern of KRT18 in colorectal cancer (CRC) remained …

[HTML][HTML] Keratin17 promotes tumor growth and is associated with poor prognosis in gastric cancer

H Hu, D Xu, X Huang, C Zhu, J Xu, Z Zhang… - Journal of …, 2018 - ncbi.nlm.nih.gov
Krt17 is a 48kDa protein member of keratin family. Previous literatures have demonstrated
Krt17 may play a promotive role in the progression of various malignancies. However, the …

KRT15 overexpression predicts poor prognosis in colorectal cancer.

X Rao, J Wang, HM Song, B Deng, JG Li - Neoplasma, 2020 - search.ebscohost.com
Abstract Keratin-15 (KRT15) is a type I keratin lacking a defined type II partner and plays a
key role in maintaining cytoplasmic stability. Recently, studies report that KRT15 is …

[HTML][HTML] Keratin 80 promotes migration and invasion of colorectal carcinoma by interacting with PRKDC via activating the AKT pathway

C Li, X Liu, Y Liu, X Liu, R Wang, J Liao, S Wu… - Cell death & …, 2018 - nature.com
Little is known about the function of Keratin 80 (KRT80), an epithelial keratin, in cancer. This
study investigated the role of KRT80 in the prognosis of colorectal carcinoma (CRC) and the …

Keratin 17 upregulation promotes cell metastasis and angiogenesis in colon adenocarcinoma

R Ji, Y Ji, L Ma, S Ge, J Chen, S Wu, T Huang… - …, 2021 - Taylor & Francis
Colon adenocarcinoma (COAD), having high malignancy and poor prognosis, is the main
pathological type of colon cancer. Previous studies show that Keratin 17 (KRT17) plays an …

Overexpression of KRT17 promotes proliferation and invasion of non-small cell lung cancer and indicates poor prognosis

Z Wang, MQ Yang, L Lei, LR Fei… - Cancer management …, 2019 - Taylor & Francis
Purpose Keratin 17 (KRT17) is a 48 KDa type I intermediate filament, which is mainly
expressed in epithelial basal cells. KRT17 has been shown to be overexpressed in many …

High KRT 8 expression promotes tumor progression and metastasis of gastric cancer

J Fang, H Wang, Y Liu, F Ding, Y Ni, S Shao - Cancer science, 2017 - Wiley Online Library
Keratin8 (KRT 8) is the major component of the intermediate filament cytoskeleton and
predominantly expressed in simple epithelial tissues. Aberrant expression of KRT 8 is …

[HTML][HTML] Keratin 17 promotes lung adenocarcinoma progression by enhancing cell proliferation and invasion

J Liu, L Liu, L Cao, Q Wen - Medical science monitor: international …, 2018 - ncbi.nlm.nih.gov
Results Both the RNA and protein levels of KRT17 were up-regulated in LAC tissues
compared to normal lung tissues. High expression of KRT17 was correlated with advanced …

[HTML][HTML] Knockdown of KRT17 by siRNA induces antitumoral effects on gastric cancer cells

M Chivu-Economescu, DL Dragu, LG Necula, L Matei… - Gastric Cancer, 2017 - Springer
Abstract Background Keratin 17 (KRT17) was shown to be an important molecular marker
for predicting the carcinogenesis, progression, and prognosis of various cancer types. Our …

[HTML][HTML] Keratin 17 activates AKT signalling and induces epithelial-mesenchymal transition in oesophageal squamous cell carcinoma

Z Liu, S Yu, S Ye, Z Shen, L Gao, Z Han, P Zhang… - Journal of …, 2020 - Elsevier
Oesophageal squamous cell carcinoma (ESCC) is an aggressive malignancy and a leading
cause of cancer-related death worldwide. Lack of effective early diagnosis strategies and …