Obesity is a metabolic disorder of increasing prevalence worldwide and a risk factor for the
development of insulin resistance (IR), metabolic syndrome and type 2 diabetes. Obesity is …

Obesity is an ongoing worldwide epidemic. Besides being a medical condition in itself,
obesity dramatically increases the risk of development of metabolic and cardiovascular …

Endothelium modulates vascular function and structure, mainly by production of nitric oxide
which protects the vasculature against the development of atherosclerosis and thrombosis …

Obesity is one of the major risk factors for the development of cardiovascular diseases. It is
characterized by excessive or abnormal accumulation of adipose tissue, including depots …

Endothelium plays a crucial role in modulating vascular function and structure, mainly by
production of nitric oxide which protects the vasculature against the development of …

Chronic inflammatory state in obesity causes dysregulation of the endocrine and paracrine
actions of adipocyte-derived factors, which disrupt vascular homeostasis and contribute to …

Obesity is associated with altered arterial homeostasis and endothelial dysfunction.
Mechanisms of disease are related to a complex interplay of metabolic and inflammatory …

Obesity is rising worldwide at an alarming rate and so is the incidence of obesity‐related
disorders, such as the metabolic syndrome, type 2 diabetes and cardiovascular diseases …

Obesity, insulin resistance, and endothelial dysfunction closely coexist throughout the
natural history of type 2 diabetes. They all can be identified not only in people with type 2 …

Morbid obesity is a chronic multifunctional disease characterized by an accumulation of fat.
Epidemiological studies have shown that obesity is associated with cardiovascular and …