Fructus Psoraleae (FP) is an edible Chinese herbal which is widely used in Asia for the
treatment of various diseases including asthma, diarrhea, and osteoporosis. This study …

抄録 Liver microsomal carboxylesterases (CES) function in the hydrolysis of a wide variety of
endogenous and xenobiotic compounds, and play an important role in drug and lipid …

Serine-dependent carboxylesterases (EC 3.1. 1.1) are found in a variety of tissues with high
activity detected in the liver. Carboxylesterases (CaE) hydrolyze aliphatic and aromatic …

An expanded series of alkyl 2-arylhydrazinylidene-3-oxo-3-polyfluoroalkylpropionates
(HOPs) 3 was obtained via Cu (OAc) 2-catalyzed azo coupling. All were nanomolar …

The polyisoprenylation pathway enzymes have been the focus of numerous studies to better
understand the roles of polyisoprenylated proteins in eukaryotic cells and to identify novel …

For substituted phenyl‐N‐butyl carbamates (1) and 4‐nitrophenyl‐N‐substituted carbamates
(2), linear relationships between values of NH proton chemical shift (δNH), pKa, and logk …

A prodrug is a pharmacologically inactive derivative of an active parent drug, and is
bioconverted to the active drug in vivo. Through chemical modification of a drug to a …

抄録 Liver microsomal carboxylesterases (EC 3.1. 1.1) function in the hydrolysis of a wide
variety of endogenous and xenobiotic compounds, and play an important role in drug and …

Carboxylesterases are thought to play an important role in drug metabolism and
detoxication of organophosphorus pesticides. Based on enzymatic studies, multiple forms of …

A full-length cDNA encoding for a putative carboxylesterase was isolated from a hamster
liver cDNA library. The cDNA consisting of 1911 base pairs contained an open reading …