Levofloxacin prophylaxis during induction therapy for pediatric acute lymphoblastic leukemia

J Wolf, LI Tang, PM Flynn, CH Pui… - Clinical Infectious …, 2017 - academic.oup.com
Background Infection is the most important cause of treatment-related morbidity and
mortality in pediatric patients treated for acute lymphoblastic leukemia (ALL). Although …

Comparative effectiveness and safety of antibiotic prophylaxis during induction chemotherapy in children with acute leukaemia: a systematic review and meta-analysis

M Yang, X Lu, L Xin, J Luo, S Diao, Z Jia… - Journal of Hospital …, 2023 - Elsevier
Background Bacterial infections are common during induction therapy in children and
adolescents with acute leukaemia and may cause infection-related mortality. Aim To …

Effectiveness of antibacterial prophylaxis during induction chemotherapy in children with acute lymphoblastic leukemia

ML Sulis, TM Blonquist, KE Stevenson… - Pediatric blood & …, 2018 - Wiley Online Library
Background Pediatric patients receiving induction chemotherapy for newly diagnosed acute
lymphoblastic leukemia (ALL) are at high risk of developing life‐threatening infections. We …

Effect of levofloxacin prophylaxis on bacteremia in children with acute leukemia or undergoing hematopoietic stem cell transplantation: a randomized clinical trial

S Alexander, BT Fisher, AH Gaur, CC Dvorak, DV Luna… - Jama, 2018 - jamanetwork.com
Importance Bacteremia causes considerable morbidity among children with acute leukemia
and those undergoing hematopoietic stem cell transplantation (HSCT). There are limited …

Randomized double blind trial of ciprofloxacin prophylaxis during induction treatment in childhood acute lymphoblastic leukemia in the WK-ALL protocol in Indonesia

PH Widjajanto, S Sumadiono, J Cloos… - Journal of Blood …, 2013 - Taylor & Francis
Objectives Toxic death is a big problem in the treatment of childhood acute lymphoblastic
leukemia (ALL), especially in low-income countries. Studies of ciprofloxacin as single agent …

Infections during induction therapy for children with acute lymphoblastic leukemia. The role of sulfamethoxazole–trimethoprim (SMX–TMP) prophylaxis.

C Rungoe, EL Malchau, LN Larsen… - Pediatric Blood & …, 2010 - Wiley Online Library
Background Bacteremias are frequent during induction therapy for acute lymphoblastic
leukemia (ALL) in children. Antibacterial prophylaxis therapy may thus be warranted. The …

Impact of reduction of therapy on infectious complications in childhood acute lymphoblastic leukemia

UB Graubner, S Porzig, N Jorch, R Kolb… - Pediatric blood & …, 2008 - Wiley Online Library
Background Infections are a major cause of morbidity and mortality in childhood acute
lymphoblastic leukemia (ALL) and only limited information is available on infectious …

A pilot study of prophylactic ciprofloxacin during delayed intensification in children with acute lymphoblastic leukemia

AA Yousef, CJH Fryer, FD Chedid… - Pediatric blood & …, 2004 - Wiley Online Library
Background We hypothesized that prophylactic administration of an appropriate antibiotic
following each delayed intensification (DI) in children with acute lymphoblastic leukemia …

[HTML][HTML] Infection-related complications during treatment for childhood acute lymphoblastic leukemia

H Inaba, D Pei, J Wolf, SC Howard, RT Hayden, M Go… - Annals of …, 2017 - Elsevier
Background Comprehensive studies on neutropenia and infection-related complications in
patients with acute lymphoblastic leukemia (ALL) are lacking. Patients and methods We …

Feasibility, efficacy, and adverse effects of outpatient antibacterial prophylaxis in children with acute myeloid leukemia

H Inaba, AH Gaur, X Cao, PM Flynn, SB Pounds… - Cancer, 2014 - Wiley Online Library
BACKGROUND Intensive chemotherapy for pediatric acute myeloid leukemia incurs the risk
of infectious complications, but the benefits of antibiotic prophylaxis remain unclear …