We have induced fresh peripheral blood K/natural killer cells to lyse a variety of target cells
by coating them with anti-Fc gamma receptor (anti-Fc gamma R)(CD16) antibody hetero …

Cloned lymphoid cell lines showing cytolytic activity were derived from natural killer (NK) cell-
enriched cell fractions obtained by fluorescence-activated cell sorting of cells that reacted …

A murine monoclonal antibody, 13.1, which blocks human natural killer (NK) cell-mediated
lysis, has been developed. Hybridoma 13.1 was derived by fusion of NS-1 cells with spleen …

We recently described a mAb 3.2. 3 (IgG1), that recognizes a 60-kD dimeric molecule
expressed exclusively on fresh and rIL-2-activated NK cells and polymorphonuclear cells …

We have isolated subsets of cells from human PBL and have investigated their abilities to
mediate lysis targeted by bispecific antibodies. Targeted cytotoxic cells were divided into two …

The simultaneous injection of monoclonal antibody 9.2. 27, directed against a chondroitin
sulfate proteoglycan preferentially expressed on human melanoma cells, and 2 X 10 (7) …

Unstimulated human peripheral blood lymphocytes were depleted of K cells, which mediate
antibody-dependent cellular cytotoxicity (ADCC) without removing NK cells, which mediate …

Natural killing (NK) in humans, as well as in other species, has been shown to be specific for
antigenic determinants present on the surfaces of a variety of tumor cells. Physical …

The relationship between the killing mechanisms of human natural killer (NK) cells, mitogen-
and mixed-lymphocyte-culture-induced activated lymphocyte killer (ALK) cells, and …

The role of major histocompatibility gene products (ie, HLA molecules) in rendering tumor
cells resistant to natural killer (NK) cell-mediated lysis was investigated by using mouse …