Engineered nanodrug targeting oxidative stress for treatment of acute kidney injury
Acute kidney injury (AKI) is a clinical syndrome characterized by a rapid decline in renal
function, and is associated with a high risk of death. Many pathological changes happen in …
function, and is associated with a high risk of death. Many pathological changes happen in …
[HTML][HTML] Nanodrugs alleviate acute kidney injury: Manipulate RONS at kidney
Q Chen, Y Nan, Y Yang, Z Xiao, M Liu, J Huang… - Bioactive materials, 2023 - Elsevier
Currently, there are no clinical drugs available to treat acute kidney injury (AKI). Given the
high prevalence and high mortality rate of AKI, the development of drugs to effectively treat …
high prevalence and high mortality rate of AKI, the development of drugs to effectively treat …
Recent Advances in Nanomaterials for the Treatment of Acute Kidney Injury
X Ba, T Ye, H Shang, Y Tong, Q Huang… - … Applied Materials & …, 2024 - ACS Publications
Acute kidney injury (AKI) is a serious clinical syndrome with high morbidity, elevated
mortality, and poor prognosis, commonly considered a “sword of Damocles” for hospitalized …
mortality, and poor prognosis, commonly considered a “sword of Damocles” for hospitalized …
Nanosystems for oxidative stress regulation in the anti-inflammatory therapy of acute kidney injury
Y Wang, H Jiang, L Zhang, P Yao, S Wang… - … in Bioengineering and …, 2023 - frontiersin.org
Acute kidney injury (AKI) is a clinical syndrome that results from a rapid decline in renal
structure or renal functional impairment with the main pathological feature of sublethal and …
structure or renal functional impairment with the main pathological feature of sublethal and …
Application of nanotechnology in acute kidney injury: From diagnosis to therapeutic implications
Acute kidney injury (AKI), a major health issue concerning~ 50% of patients treated in
intensive care units, generally leads to severe renal damage associated with high mortality …
intensive care units, generally leads to severe renal damage associated with high mortality …
[HTML][HTML] Recent advances in nanotherapeutics for the treatment and prevention of acute kidney injury
H Yu, D Liu, G Shu, F Jin, Y Du - Asian Journal of Pharmaceutical Sciences, 2021 - Elsevier
Acute kidney injury (AKI) is a serious kidney disease without specific medications currently
except for expensive dialysis treatment. Some potential drugs are limited due to their high …
except for expensive dialysis treatment. Some potential drugs are limited due to their high …
Biodegradable Self‐Assembled Ultrasmall Nanodots as Reactive Oxygen/Nitrogen Species Scavengers for Theranostic Application in Acute Kidney Injury
Acute kidney injury (AKI) is frequently triggered by abundant reactive oxygen/nitrogen
species (RONS) and leads to high morbidity and mortality in clinic. Unfortunately, the current …
species (RONS) and leads to high morbidity and mortality in clinic. Unfortunately, the current …
Delivering drugs to tubular cells and organelles: the application of nanodrugs in acute kidney injury
Z Li, X Fan, J Fan, W Zhang, J Liu, B Liu, H Zhang - Nanomedicine, 2023 - Taylor & Francis
Acute kidney injury (AKI) is a common clinical syndrome with limited treatment options and
high mortality rates. Proximal tubular epithelial cells (PTECs) play a key role in AKI …
high mortality rates. Proximal tubular epithelial cells (PTECs) play a key role in AKI …
Renal Nano-drug delivery for acute kidney Injury: Current status and future perspectives
Acute kidney injury (AKI) causes considerable morbidity and mortality, particularly in the
case of post-cardiac infarction or kidney transplantation; however, the site-specific …
case of post-cardiac infarction or kidney transplantation; however, the site-specific …
Inflammation-sensing catalase-mimicking nanozymes alleviate acute kidney injury via reversing local oxidative stress
Background The reactive oxygen species (ROS) and inflammation, a critical contributor to
tissue damage, is well-known to be associated with various disease. The kidney is …
tissue damage, is well-known to be associated with various disease. The kidney is …
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