The receptors for tumor necrosis factor (TNF) exist in cell-associated as well as soluble
forms, both binding specifically to TNF. Since the soluble forms of TNF receptors (sTNF-Rs) …

Tumor necrosis factor (TNF) is a pleiotropic mediator of inflammatory responses. A cysteine-
rich, highly glycosylated 30-kD TNF-binding protein (TNF-BP) purified from urine may have a …

Tumor necrosis factor (TNF) is a 17-kDa protein produced by monocytes and a wide variety
of other cell types in response to endotoxin and other cytokines. In contrast, lymphotoxin (LT) …

Tumor necrosis factor (TNF) is the name given to a serum-derived factor that is cytotoxic for
many transformed cell lines in vitro and causes the necrosis of certain tumors in vivo …

Intestinal epithelial barrier function and Crohn's disease are intimately related. An impaired
barrier in association with active inflammation leads to increased exposure of the mucosal …

Plasma membranes were isolated from thioglycolate-induced peritoneal mouse
macrophages and tested directly in a 51Cr-release assay against WEHI 164 tumor cells …

The gene for tumor necrosis factor, TNF, was expressed in 45 out of 63 biopsies of human
epithelial ovarian cancer. In serous tumors, there was a positive correlation between level of …

Three different antibodies against a human TNF receptor (htr-1, htr-5, and htr-9) have been
examined for their binding pattern to U937 cells and ability to mimic TNF-alpha activity in …

Tumor necrosis factor (TNF)-α is a potent pro-inflammatory and pathological cytokines in
inflammatory diseases such as rheumatoid arthritis and inflammatory bowel diseases. Anti …

Tumor necrosis factor (TNF) came to birth in a strange way. It made its entry into the world of
biology and medicine when Lloyd Old discovered that the capacity to induce, in vivo and in …