Estrogen receptor β is coexpressed with ERα and PR and associated with nodal status, grade, and proliferation rate in breast cancer

TAH Järvinen, M Pelto-Huikko, K Holli, J Isola - The American journal of …, 2000 - Elsevier
The role of estrogen (ER) and progesterone receptors (PR) in breast cancer is well
established. Identification of the second human estrogen receptor, the estrogen receptor β …

Estrogen receptors and proliferation markers in primary and recurrent breast cancer

EV Jensen, G Cheng, C Palmieri… - Proceedings of the …, 2001 - National Acad Sciences
To elucidate the clinical importance of estrogen receptor (ER) β in breast cancer, 29 archival
primary breast cancer specimens, six locally recurrent cancers, and five benign mammary …

Clinical significance of the expression of estrogen receptors α and β for endocrine therapy of breast cancer

H Iwase, Z Zhang, Y Omoto, H Sugiura… - Cancer chemotherapy …, 2003 - Springer
The assessment of the estrogen receptor (ER) α and the progesterone receptor (PgR) in
breast cancer tissues is important for discriminating between hormone-dependent and …

Estrogen receptor β protein in human breast cancer: correlation with clinical tumor parameters

SAW Fuqua, R Schiff, I Parra, JT Moore, SK Mohsin… - Cancer research, 2003 - AACR
The recent discovery of a second estrogen receptor (ER), designated ERβ, raises pressing
questions about its role in estrogen regulation of human breast cancer cells and its …

Oestrogen receptors α and β show different associations to clinicopathological parameters and their co-expression might predict a better response to endocrine …

S Borgquist, C Holm, M Stendahl… - Journal of clinical …, 2008 - jcp.bmj.com
Aims: The majority of all breast cancers are hormone responsive, traditionally defined by the
expression of oestrogen receptor (ER) α and/or progesterone receptors. In contrast to ERα …

Clinical value of the wild-type estrogen receptor β expression in breast cancer

Y Omoto, S Inoue, S Ogawa, T Toyama, H Yamashita… - Cancer letters, 2001 - Elsevier
To estimate the clinical value of estrogen receptor (ER) β expression in breast cancer we
used an immunohistochemical method to detect the wild-type ERβ in 88 primary breast …

Coexpression of estrogen receptor α and β: poor prognostic factors in human breast cancer?

V Speirs, AT Parkes, MJ Kerin, DS Walton, PJ Carleton… - Cancer research, 1999 - AACR
The cloning of a second estrogen receptor (ER), ERβ, has prompted a reevaluation of the
role of ERs in breast cancer. The aim of this study was to determine the expression of both …

Expression of estrogen receptor-β in normal mammary and tumor tissues: is it protective in breast carcinogenesis?

BW Park, KS Kim, MK Heo, SS Ko, KS Lee… - Breast cancer research …, 2003 - Springer
Using messenger RNA (mRNA) in situ hybridization, we investigated estrogen receptor-β
(ERβ) mRNA levels in normal mammary, benign breast tumor (BBT), breast cancer (BC) …

Nuclear and cytoplasmic expression of ERβ1, ERβ2, and ERβ5 identifies distinct prognostic outcome for breast cancer patients

AM Shaaban, AR Green, S Karthik, Y Alizadeh… - Clinical Cancer …, 2008 - AACR
Purpose: Previous conflicting results about the prognostic significance of estrogen receptor
(ER)-β in breast cancer may be explained by contribution of isoforms, of which five exist. Our …

Decreased expression of estrogen receptor β protein in proliferative preinvasive mammary tumors

P Roger, ME Sahla, S Mäkelä, JA Gustafsson… - Cancer research, 2001 - AACR
To understand the significance of estrogen receptor β (ERβ) in mammary carcinogenesis,
we evaluated the expression of ERβ in preinvasive mammary tumors. The percentage of …