Background: Mutations in the tyrosine kinase (TK) domain of the epidermal growth factor
receptor (EGFR) gene in lung cancers are associated with increased sensitivity of these …

Purpose: Activating somatic mutations in the epidermal growth factor receptor (EGFR) gene
are present in a small subset of lung adenocarcinomas. These mutations cluster in specific …

Recently it has been reported that mutations in the tyrosine kinase domain of the epidermal
growth factor receptor (EGFR) gene occur in a subset of patients with lung cancer showing a …

Somatic mutations in the tyrosine kinase (TK) domain of the epidermal growth factor receptor
(EGFR) gene in lung cancers have generated enormous interest, because they predict for …

Somatic mutations in the tyrosine kinase (TK) domain of the epidermal growth factor receptor
(EGFR) gene are reportedly associated with sensitivity of lung cancers to gefitinib (Iressa) …

Introduction The discovery that somatic mutations in the epidermal growth factor receptor
(EGFR) gene are associated with sensitivity to the EGFR tyrosine kinase inhibitors (TKIs) in …

Purpose: It has been reported that the mutations of epidermal growth factor receptor (EGFR)
are detected in lung cancers. Studies of EGFR mutations in large numbers of patients' …

The epidermal growth factor receptor (EGFR), and its family members play an important role
in the development and progression of lung cancers. It has been reported that somatic …

Epidermal growth factor receptor (EGFR) mutations are a potential predictor of the
effectiveness of EGFR inhibitors for the treatment of lung cancer. Although EGFR mutations …

We evaluated somatic genetic alterations in the kinase domain of the EGFR gene in the
tumors of 219 non–small cell lung cancer patients of primarily Caucasian and African …