Neural tube defects (NTDs) are a heterogeneous set of malformations attributed to
disruption in normal neural tube closure during early embryogenesis. An in‐depth …

Neural tube defects (NTDs) are a group of often severe congenital malformations of the
central nervous system that arise early in human embryogenesis when the neural tube, the …

Every year nearly 6 percent of children worldwide are born with a serious congenital
malformation, resulting in death or lifelong disability. In the United States, birth defects …

Background Neural tube defects (NTD) are among the most common defects affecting 1:
1000 births. They are caused by a failure of neural tube closure during development. Their …

Neural tube defects (NTDs) are congenital birth defects classified according to their resulting
morphological characteristics in newborn patients. Current diagnosis of NTDs relies largely …

It is well established that the regulation of epigenetic factors, including chromatic
reorganization, histone modifications, DNA methylation, and miRNA regulation, is critical for …

Neural tube defects (NTDs) are a spectrum of severe congenital malformations of fusion
failure of the neural tube during early embryogenesis. Evidence on aberrant DNA …

Neural tube defects (NTD) result from complex mechanisms between genes, nutrition and
environment. The identification of genetic predictors by genome exome sequencing and …

In the embryonic and adult brain, neural stem cells proliferate and give rise to neurons and
glia through highly regulated processes. Epigenetic mechanisms—including DNA and …

Neural tube defects (NTDs) are a classic example of preventable birth defects for which
there is a proven‐effective intervention, folic acid (FA); however, further methods of …