Lung ultrasound B-lines in the evaluation of the extent of interstitial lung disease in systemic sclerosis

C Bruni, L Mattolini, L Tofani, L Gargani, N Landini… - Diagnostics, 2022 - mdpi.com
Background: Chest computed tomography (CT) is the gold standard for the evaluation of
systemic sclerosis-related interstitial lung disease (SSc-ILD). Lung ultrasound (LUS) is a …

Systemic sclerosis associated interstitial lung disease: a conceptual framework for subclinical, clinical and progressive disease

D Roofeh, KK Brown, EA Kazerooni, D Tashkin… - …, 2023 - academic.oup.com
Objectives To establish a framework by which experts define disease subsets in systemic
sclerosis associated interstitial lung disease (SSc-ILD). Methods A conceptual framework for …

Association of computed tomography densitometry with disease severity, functional decline, and survival in systemic sclerosis-associated interstitial lung disease

DC Saldana, CJ Hague, D Murphy… - Annals of the …, 2020 - atsjournals.org
Rationale: Measuring disease extent and progression of systemic sclerosis–associated
interstitial lung disease (SSc-ILD) is challenging, with recent studies suggesting potential …

Association of interferon‐and transforming growth factor β–regulated genes and macrophage activation with systemic sclerosis–related progressive lung fibrosis

RB Christmann, P Sampaio‐Barros… - Arthritis & …, 2014 - Wiley Online Library
Objective Systemic sclerosis (SSc)–related interstitial lung disease (ILD) is one of the
leading causes of mortality. We undertook this study to analyze the gene expression of lung …

Biomarkers to identify ILD and predict lung function decline in scleroderma lung disease or idiopathic pulmonary fibrosis.

B Kennedy, P Branagan, F Moloney… - … vasculitis, and diffuse …, 2015 - europepmc.org
Background SSc-ILD and IPF demonstrate significant morbidity and mortality. Predicting
disease progression is challenging in both diseases. Objectives We sought a serum …

Predictors of lung function test severity and outcome in systemic sclerosis-associated interstitial lung disease

N Le Gouellec, A Duhamel, T Perez, AL Hachulla… - PLoS …, 2017 - journals.plos.org
Systemic sclerosis-related interstitial lung disease (SSc-ILD) is the leading cause of death in
SSc. In this study, we aimed to describe the baseline severity and evolution of forced vital …

Detection and monitoring of interstitial lung disease in patients with systemic sclerosis

SA Khanna, JW Nance, SA Suliman - Current Rheumatology Reports, 2022 - Springer
Abstract Purpose of Review Interstitial lung disease (ILD) is a common manifestation of
systemic sclerosis (SSc). We explore the importance of early detection, monitoring, and …

CT features of lung disease in patients with systemic sclerosis: comparison with idiopathic pulmonary fibrosis and nonspecific interstitial pneumonia

SR Desai, S Veeraraghavan, DM Hansell… - Radiology, 2004 - pubs.rsna.org
PURPOSE: To evaluate computed tomographic (CT) patterns of lung disease in patients
with systemic sclerosis (SSc) and compare them with CT appearance in patients with biopsy …

Interstitial lung disease associated with systemic sclerosis (SSc-ILD)

V Cottin, KK Brown - Respiratory research, 2019 - Springer
Abstract Background Systemic sclerosis (SSc) is a rare connective tissue disease with a
heterogeneous clinical course. Interstitial lung disease (ILD) is a common manifestation of …

Computed tomography predictors of mortality or disease progression in systemic sclerosis–interstitial lung disease: a systematic review

N Landini, M Orlandi, C Bruni, E Carlesi, C Nardi… - Frontiers in …, 2022 - frontiersin.org
Objective Although interstitial lung disease (ILD) is a major cause of morbidity and mortality
in systemic sclerosis (SSc), its prognostication remains challenging. Given that CT …