[HTML][HTML] Therapeutic Categories

BE Johnson - expertperspectives.com
Circulating tumor DNA (ctDNA) testing is widely used in oncology to identify genomic
alterations. Our featured experts review the strengths and limitations of ctDNA testing in non …

Circulating tumor DNA testing in advanced non-small cell lung cancer

EJ Moding, M Diehn, HA Wakelee - Lung Cancer, 2018 - Elsevier
Circulating tumor DNA (ctDNA) shed from cancer cells into the peripheral blood can be non-
invasively collected and tested for the presence of tumor-specific mutations. Mutations …

Circulating tumor DNA in non–small-cell lung cancer: a primer for the clinician

AP Singh, H Cheng, X Guo, B Levy… - JCO Precision …, 2017 - ascopubs.org
Circulating tumor DNA (ctDNA) consists of short, double-stranded DNA fragments that are
released into the circulation by tumor cells. With the advent of newer molecular platforms …

Circulating tumor DNA detection in MRD assessment and diagnosis and treatment of non-small cell lung cancer

X Fang, S Yu, Y Jiang, Y Xiang, K Lu - Frontiers in Oncology, 2022 - frontiersin.org
Circulating tumor DNA (ctDNA) has contributed immensely to the management of
hematologic malignancy and is now considered a valuable detection tool for solid tumors …

The role of circulating tumor DNA in lung cancer: mutational analysis, diagnosis, and surveillance now and into the future

KA Scilla, C Rolfo - Current Treatment Options in Oncology, 2019 - Springer
Opinion statement Isolation and analysis of circulating tumor DNA (ctDNA) have emerged as
an effective and promising tool for genomic profiling in non-small cell lung cancer. Analysis …

Challenges in implementing circulating tumor DNA analyses in lung cancer research

AL Ottestad - 2023 - ntnuopen.ntnu.no
Lung cancer is the leading cause of cancer-related deaths worldwide, including Norway.
This study focused on non-small cell lung cancer (NSCLC), the most common subtype, and …

Longitudinal ctDNA profiling in precision oncology and immunο-oncology

P Filis, I Kyrochristos, E Korakaki, EG Baltagiannis… - Drug Discovery …, 2023 - Elsevier
Highlights•Serial circulating tumor DNA profiling is emerging as biomarker to guide
treatment and monitor the disease.•In metastatic disease, liquid multigene assays have …

Clinical validity and utility of circulating tumor DNA (ctDNA) testing in advanced non-small cell lung cancer (aNSCLC): a systematic literature review and meta-analysis

C Chen, MP Douglas, MV Ragavan, KA Phillips… - medRxiv, 2023 - medrxiv.org
Purpose: Circulating tumor DNA (ctDNA) testing has become a promising tool to guide first-
line (1L) targeted treatment for advanced non-small cell lung cancer (aNSCLC). This study …

A scenario‐drafting study to explore potential future implementation pathways of circulating tumor DNA testing in oncology

A Kramer, C Rubio‐Alarcón… - Molecular …, 2023 - Wiley Online Library
Circulating tumor DNA (ctDNA) detection has multiple promising applications in oncology,
but the road toward implementation in clinical practice is unclear. We aimed to support the …

[HTML][HTML] Circulating tumor DNA analysis in the era of precision oncology

R Said, N Guibert, GR Oxnard, AM Tsimberidou - Oncotarget, 2020 - ncbi.nlm.nih.gov
The spatial and temporal genomic heterogeneity of various tumor types and advances in
technology have stimulated the development of circulating tumor DNA (ctDNA) genotyping …